Protein Alignment MsR1 and sprr-2

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_510455.2
• Gene: sprr-2 / 181575
• WormBaseID: WBGene00009629
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 106/428 - (24%)
• Similarity: 187/428 - (43%)
• Gaps: 119/428 - (27%)

  Fly    22 TSYKNM----HGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTI 82
            |.:.|:    :|.:..::.:....||....:||:::.|.:|||.:|..:|:|:|.|.|..:|:|:
 Worm    51 TQFDNLEIVVYGQIFPILVLFAVFANAAVALVLSKKHMITPTNVVLKYMAIAELLVGLVPLPWTL 115

  Fly    83 HDYILTDSLPREEKLSYSWACFIKFHSI--FAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCG 145
            . :....::....:|.. |.|:::.:|:  |..|.|.|::||||.||..||:::.:|..:|..|.
 Worm   116 F-FFSMGNIKETHRLEL-WWCYLQKYSMDAFPPVFHMIAMWLTVLLAAQRYVSISHPLHSRSACN 178

  Fly   146 MR-----TTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELL 205
            ::     |.|||:|:  .:|.|..|               .|...:.::.     ::..:.|
 Worm   179 VKNVRLATMIITVTS--FLCGLPKS---------------FDYEYETVHG-----WIYSHGN--- 218

  Fly   206 SARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNV--TVY-RLYHSDLALHNAS 267
                                |..||:.:.        .|:.::.|:  ||| .:|....||
 Worm   219 --------------------WTYASSCVM--------MPTAILTNMGQTVYFNIYFWTRAL---- 251

  Fly   268 LQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAAD 332
                .|:|       :|...|.:|:..||..:..|:||:.:|..:
 Worm   252 ----GFII-------LPSFLLVLLNGLLIKGIRRAQRRKLRLLRE-------------------- 285

  Fly   333 RPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGI-MGLLNAVLGDVFYLQCYLRLSDLMDI 396
               |.|:...:::.::.|:.||:|::.:|||...||.| ||||  .:.:.|.::..: |......
 Worm   286 ---KRSEEAARQRDSNSTSLMLVAIVSIFLIVNLPQAIFMGLL--CVCETFTIKIPI-LEGTFPA 344

  Fly   397 LALINSS--------INFILYCSMSKQFRTTFTLLFRP 426
            :.||.|:        |||.:||.||..||.||.|||.|
 Worm   345 VFLIASNMIVIATYPINFGIYCFMSSSFRQTFKLLFCP 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	98/410 (24%)
		TM helix 1	28..53	CDD:410630	5/24 (21%)
		TM helix 2	59..84	CDD:410630	10/24 (42%)
		TM helix 3	105..135	CDD:410630	13/31 (42%)
		TM helix 4	147..167	CDD:410630	8/24 (33%)
		TM helix 5	269..294	CDD:410630	5/24 (21%)
		TM helix 6	345..375	CDD:410630	13/30 (43%)
		TM helix 7	388..413	CDD:410630	9/32 (28%)
sprr-2	NP_510455.2	7tmA_FMRFamide_R-like	59..376	CDD:410630	98/412 (24%)
		TM helix 1	60..86	CDD:410630	5/25 (20%)
		TM helix 2	92..117	CDD:410630	10/25 (40%)
		TM helix 3	138..168	CDD:410630	13/29 (45%)
		TM helix 4	180..200	CDD:410630	7/21 (33%)
		TM helix 5	242..267	CDD:410630	8/39 (21%)
		TM helix 6	295..325	CDD:410630	12/29 (41%)
		TM helix 7	344..369	CDD:410630	8/24 (33%)