Protein Alignment MsR1 and dmsr-7

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_504431.2
• Gene: dmsr-7 / 178922
• WormBaseID: WBGene00016428
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 144/538 - (26%)
• Similarity: 237/538 - (44%)
• Gaps: 144/538 - (26%)

  Fly    19 NFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTI 82
            :|...|:.:||||.:::|:.|...|.:::.||:|..|| |..|.|||.:||.|:..|..|:.|.|
 Worm    26 HFQRWYQPIHGYVCVLICVFGIFTNFVHVAVLSRPNMRNSAVNCILTAVAVCDIGTMASYLIYII 90

  Fly    83 HDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMR 147
            | ::|..:.......::||..|:.:|.:.:..|||.|:||.|.:|..|.:.:.....|..|  .|
 Worm    91 H-FVLRRNNSCTPTFTHSWLQFLLWHVVLSITLHTTSLWLAVAMAFIRRMTLRVTALNSQW--QR 152

  Fly   148 TTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAAL 212
            ...     |:.:|:     .:|::..:      |.:...:::.|...:     .|:....:|...
 Worm   153 PKF-----AWKLCL-----GIYMVVFV------LCIPNMLVHEIARVE-----GNDWRPGKTCQK 196

  Fly   213 NATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYS 277
            .|:..|.|:...:..:|:|                               ::|..|......:..
 Worm   197 FASNYSEPVYTFMVSHAAT-------------------------------INNCRLFKWNIWMIG 230

  Fly   278 VVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLE 342
            ::.|:||||.|..||..|:..:.:|::.|:||||.|     ||.:             .:||.|:
 Worm   231 ILFKIIPCILLIFLSFGLVSKIRDAEKHRRKLTSVP-----SNAS-------------TDSKPLK 277

  Fly   343 KEKQT-DRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINF 406
            |:..| ||||.||:.:||:||||||||||:.:|.|:.....:...|..:.|::|:|:|:|||:||
 Worm   278 KKNGTSDRTTLMLVVILLVFLITEFPQGIISILCAIFTTDVHRYLYFYIGDVLDLLSLVNSSVNF 342

  Fly   407 ILYCSMSKQFRTTFTLLFRPKFLDKWLPVAQDEMAAARAERSAVAPVLEKGRQQPQVVMASTTTN 471
            :|||.||.::|.||           |                             :|::.|....
 Worm   343 VLYCVMSSRYRQTF-----------W-----------------------------EVIIPSWACG 367

  Fly   472 ITQVTNLXHRRSRGRRTLLSRLL--SVLKRGRRRSSGEGGGVGGGGAPLAGNDAVEPA------F 528
            :...       .||..|.||:|.  :.|:.||::|.          .|||...  |||      :
 Worm   368 LWTT-------RRGSPTELSQLQLNNSLRLGRKQSY----------TPLATEP--EPARNEYWRY 413

  Fly   529 QAIVVVVDKVSGATENQL 546
            :|  .|.|..:.:.|:||
 Worm   414 EA--SVSDNQNSSREHQL 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	115/393 (29%)
		TM helix 1	28..53	CDD:410630	9/24 (38%)
		TM helix 2	59..84	CDD:410630	11/24 (46%)
		TM helix 3	105..135	CDD:410630	10/29 (34%)
		TM helix 4	147..167	CDD:410630	3/19 (16%)
		TM helix 5	269..294	CDD:410630	8/24 (33%)
		TM helix 6	345..375	CDD:410630	19/30 (63%)
		TM helix 7	388..413	CDD:410630	12/24 (50%)
dmsr-7	NP_504431.2	7tmA_FMRFamide_R-like	33..356	CDD:410630	115/395 (29%)
		TM helix 1	34..60	CDD:410630	9/25 (36%)
		TM helix 2	67..92	CDD:410630	12/25 (48%)
		TM helix 3	112..142	CDD:410630	10/29 (34%)
		TM helix 4	154..174	CDD:410630	4/35 (11%)
		TM helix 5	222..247	CDD:410630	8/24 (33%)
		TM helix 6	281..311	CDD:410630	19/29 (66%)
		TM helix 7	324..349	CDD:410630	12/24 (50%)