Protein Alignment MsR1 and gpr139

DIOPT Version :9

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001308927.1
• Gene: gpr139 / 100493863
• XenbaseID: XB-GENE-6042001
• Length: 348
• Species: Xenopus tropicalis
• Alignment Length: 395
• Identity: 93/395 - (23%)
• Similarity: 156/395 - (39%)
• Gaps: 138/395 - (34%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTR---REMRSPTNAILTGLAVADLAVM--LEYIPYTIHDYILTD 89
            |.|:::| ||..||.|.:|:|::   |..:|..|.:| .||.||:.|:  :.::.:.:.|:||..
 Frog    27 YYSILLC-LGLPANILTVIILSQLVARRQKSSYNYLL-ALAAADIMVLFFIVFVDFLLEDFILNK 89

  Fly    90 SLPRE-EKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITI 153
            .:|:. :|:..    .::|.||     || |||:||.|.:.|||||.:|...........|...|
 Frog    90 QMPQMLDKIIE----VLEFSSI-----HT-SIWITVPLTIDRYIAVCHPLTYHTVSFPARTRKVI 144

  Fly   154 TTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTS 218
            .:.|:.|.|                          .|||...:
 Frog   145 VSVYITCFL--------------------------TSIPYYWW---------------------- 161

  Fly   219 APLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVIKLI 283
                ..:|:..   .|||:                  ::|..:.:|       .|.:|     |:
 Frog   162 ----PNIWIED---YTSTS------------------VHHILIWIH-------CFTVY-----LV 189

  Fly   284 PCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTD 348
            ||....:|:     :::..|.:||   |.....|.|.|
 Frog   190 PCSIFFVLN-----SIIVYKLQRK---SNFRLRGYSTG--------------------------- 219

  Fly   349 RTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYCSMS 413
            :||.:|.::..:|.|...|:.||.|.:..:..:........::|:.::|||:|::|||.|||.:|
 Frog   220 KTTAILFSITSIFAILWAPRIIMILYHLYVSPIHNSWLVHIVTDIANMLALLNTAINFFLYCFIS 284

  Fly   414 KQFRT 418
            |:|||
 Frog   285 KRFRT 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tm_4	30..427	CDD:304433	93/395 (24%)
gpr139	NP_001308927.1	7tmA_GPR139	22..291	CDD:320585	93/395 (24%)
		TM helix 1	23..49	CDD:320585	10/22 (45%)
		TM helix 2	57..82	CDD:320585	7/25 (28%)
		TM helix 3	96..126	CDD:320585	16/39 (41%)
		TM helix 4	138..158	CDD:320585	7/45 (16%)
		TM helix 5	175..200	CDD:320585	8/41 (20%)
		TM helix 6	216..248	CDD:320585	11/58 (19%)
		TM helix 7	259..284	CDD:320585	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4738
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X861
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060