Protein Alignment MsR2 and Gpr142

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001385802.1
• Gene: Gpr142 / 501735
• RGDID: 1559926
• Length: 348
• Species: Rattus norvegicus
• Alignment Length: 411
• Identity: 73/411 - (17%)
• Similarity: 140/411 - (34%)
• Gaps: 163/411 - (39%)

  Fly    28 YFSLIVCILGTIANTLNIIVLTRREMRS--PTNAILTGLAVADLA--VMLEYIPYTVHDYILSVR 88
            |:|:::. ||...|.|..:||.|..:|:  |:...|..|..:|:.  |::.:|.:.:...:|:.:
  Rat    52 YYSVLLS-LGLPVNVLTTVVLARLAVRTKKPSYHYLLALTASDIVTQVVIVFIGFLLQGAVLARQ 115

  Fly    89 LPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAVSYPQRNRIWCGMRTTLITIAT 153
            :|:         ..::..::.....:..|:|:.|...|.||.|:..|.|:|.......|...||.
  Rat   116 VPQ---------AVVRTANILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPGRTHRAIAA 171

  Fly   154 AYVVCVLVVSP---WLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNRQDEVTMQVMSSTTPD 215
            ...|.:|...|   ||                                    :|.......:|.|
  Rat   172 VLSVTLLTGIPFYWWL------------------------------------DVWRDADPPSTMD 200

  Fly   216 --VSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKLYHSALALRDRQFRN 278
              :.||
  Rat   201 KLLKWA----------------------------------------------------------- 206

  Fly   279 ATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPIVNGKVVIPTQPKSCK 343
                 :.:::..|||....:.:..:|   |..::|       ....:||.::
  Rat   207 -----HCLIVYFIPCNVFLVTNSAII---LRLRKR-------GQRGLQPWMS------------- 243

  Fly   344 LLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLGDAFFL------QCYLKLSDLMDILA 402
                     ::|.:||.|..||.:...|:     ::|:|...:..      :.:|.| |:.::||
  Rat   244 ---------KSTAILLGVTSLFALLWAPR-----ISVMLYHLYVAPVHRDWRVHLAL-DIANMLA 293

  Fly   403 LINSSINFILYCSMSRQFRST 423
            ::|:::||.|||.:|:.||:|
  Rat   294 MLNTAVNFGLYCFISKTFRAT 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	73/411 (18%)
		TM helix 1	25..51	CDD:410630	8/22 (36%)
		TM helix 2	57..82	CDD:410630	5/26 (19%)
		TM helix 3	103..133	CDD:410630	7/29 (24%)
		TM helix 4	145..165	CDD:410630	6/22 (27%)
		TM helix 5	263..302	CDD:410630	3/38 (8%)
		TM helix 6	349..379	CDD:410630	7/29 (24%)
		TM helix 7	392..417	CDD:410630	11/24 (46%)
Gpr142	NP_001385802.1	7tm_GPCRs	47..315	CDD:475119	73/411 (18%)
		TM helix 1	49..73	CDD:410628	8/21 (38%)
		TM helix 2	83..105	CDD:410628	5/21 (24%)
		TM helix 3	122..144	CDD:410628	3/21 (14%)
		TM helix 4	167..183	CDD:410628	4/15 (27%)
		TM helix 5	201..224	CDD:410628	5/86 (6%)
		TM helix 6	246..268	CDD:410628	8/26 (31%)
		TM helix 7	283..308	CDD:410628	11/25 (44%)