Protein Alignment MsR2 and MsR1

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 333/556 - (59%)
• Similarity: 394/556 - (70%)
• Gaps: 51/556 - (9%)

  Fly     4 NMSQPHYCGTGIDDFHTNYKYFHGYFSLIVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVAD 68
            |.::|.|||:|:|:|||:||..|||.||:||||||||||||||||||||||||||||||||||||
  Fly     6 NETEPLYCGSGMDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVAD 70

  Fly    69 LAVMLEYIPYTVHDYILSVRLPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAVS 133
            |||||||||||:|||||:..|||||:|||||||||||||:|.||||||||||||||||||||||.
  Fly    71 LAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVG 135

  Fly   134 YPQRNRIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDY 198
            |||:||:|||||||:|||.||||||||||||.|||:|||.::::.||.|||.|.|:|::||::||
  Fly   136 YPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDY 200

  Fly   199 NRQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSL-LSLTTVIPLTTLSTGVTTSS----SLGERN 258
            ..      :::|:.|.         :.|.|..|. |:.|..:..:||.|..||::    |...||
  Fly   201 RN------ELLSARTA---------ALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRN 250

  Fly   259 VTVYKLYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACH--- 320
            ||||:||||.|||.:...:|||||||||:||||||.||||||||||.||||||||||.|...
  Fly   251 VTVYRLYHSDLALHNASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPAT 315

  Fly   321 --AANDMQPIVNGKVVIPTQP-KSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLL 382
              |:|..:...|||..  .:| |:.|.||||||||||||||||||||||:||||||||||||.:|
  Fly   316 PGASNGTKSPANGKAA--DRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVL 378

  Fly   383 GDAFFLQCYLKLSDLMDILALINSSINFILYCSMSRQFRSTFALLFRPRWLDKWLPLSQHDGEGR 447
            ||.|:|||||:||||||||||||||||||||||||:|||:||.|||||::||||||::|.:....
  Fly   379 GDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLFRPKFLDKWLPVAQDEMAAA 443

  Fly   448 VGGSGGLGGYGGYGRQRLLHTDAVSKSMAIDLGLTTQVTNV-XQESSGRAAM------------- 498
            ......:......|||:   ...|..|...::   |||||:  :.|.||..:
  Fly   444 RAERSAVAPVLEKGRQQ---PQVVMASTTTNI---TQVTNLXHRRSRGRRTLLSRLLSVLKRGRR 502

  Fly   499 -SAAAGGAAASVALALAATDVDGCPPATDAAVSTND 533
             |:..||........||..  |...||..|.|...|
  Fly   503 RSSGEGGGVGGGGAPLAGN--DAVEPAFQAIVVVVD 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	283/410 (69%)
		TM helix 1	25..51	CDD:410630	22/25 (88%)
		TM helix 2	57..82	CDD:410630	23/24 (96%)
		TM helix 3	103..133	CDD:410630	27/29 (93%)
		TM helix 4	145..165	CDD:410630	17/19 (89%)
		TM helix 5	263..302	CDD:410630	28/38 (74%)
		TM helix 6	349..379	CDD:410630	28/29 (97%)
		TM helix 7	392..417	CDD:410630	23/24 (96%)
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	283/408 (69%)
		TM helix 1	28..53	CDD:410630	22/24 (92%)
		TM helix 2	59..84	CDD:410630	23/24 (96%)
		TM helix 3	105..135	CDD:410630	27/29 (93%)
		TM helix 4	147..167	CDD:410630	17/19 (89%)
		TM helix 5	269..294	CDD:410630	21/24 (88%)
		TM helix 6	345..375	CDD:410630	28/29 (97%)
		TM helix 7	388..413	CDD:410630	23/24 (96%)