Protein Alignment MsR2 and srw-42

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001023799.1
• Gene: srw-42 / 3565714
• WormBaseID: WBGene00005789
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 97/458 - (21%)
• Similarity: 176/458 - (38%)
• Gaps: 128/458 - (27%)

  Fly     2 VTNMSQPHYCGTGID-----DFHTNYKYFHGYF-------SLIVCILGTIANTLNIIVLTRREMR 54
            ::|||...|..:..|     :|..:::.|.|..       |:::.::|...|..::.||||:.:|
 Worm     1 MSNMSNYQYSDSKFDADESNNFLVSFEVFVGKLEQYIDLASVVISVVGFFTNIFHLAVLTRKSIR 65

  Fly    55 SPTNAI-LTGLAVADLAVMLEYIP------YTVHDYILSVRL------PREEQLSYSWACFIKFH 106
            :.:..| |.|:|:.||..|:..|.      |.|   :||:.:      ||    ||....|....
 Worm    66 NSSVFIFLIGIAICDLVRMISIIVSKSPIFYRV---LLSLFIDSTCFTPR----SYLAMIFDLIS 123

  Fly   107 SVFPQVLHTISIWLTVTLAVWRYIAVSYPQRNRIWCGMRTTLITIATAYVVCVLVVSPWLYLVTA 171
            ::...:...:|:||.|.:.::|.:.:.||...||     ::|:|..:.  :|.:
 Worm   124 NILEIISLDLSVWLAVFMTIFRVLVIRYPFNKRI-----SSLVTSKSG--LCTV----------- 170

  Fly   172 IAKFLETLDANGKTIASVPLSQYILDYNRQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLT 236
                             :|||..|..:.     .:.....|...||...||....|...:...:.
 Worm   171 -----------------IPLSIIIFPFG-----LLYYFQVTIRPVSIWKPSSDCLGFQSNFFQIN 213

  Fly   237 TVIPLTTLSTGVTTSSSLGERNVTVYKLYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSV 301
            .....|.||..:.|.        |:..:.|                :..||.||||...|.:.:.
 Worm   214 YKFSATELSGVLGTD--------TIETMIH----------------VDGVLFKLIPSIVLLVATS 254

  Fly   302 RLIGALLEAKRRRKILACHAANDMQPIVNGKVVIPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFL 366
            .|:..:    |:.|                |.:...:.||.|        |.||:::..|...||
 Worm   255 VLVFEI----RKHK----------------KTIWAQRNKSNK--------DWTTKLVFFVTFTFL 291

  Fly   367 VTEFPQGIMGLLNVLLGDAFFLQCY-LKLSDLMDILALINSSINFILYCSMSRQFRST---FALL 427
            :...||||..::...:.:...|:.. :.|..:...|:::|.:|:|:::..||.::|.|   ..|.
 Worm   292 IAIVPQGIAYIIMFKMAEIPILRIIAMSLPSVFSFLSVVNGTIHFLIFYFMSSEYRMTAKHMCLF 356

  Fly   428 FRP 430
            ::|
 Worm   357 WKP 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	89/423 (21%)
		TM helix 1	25..51	CDD:410630	8/32 (25%)
		TM helix 2	57..82	CDD:410630	10/31 (32%)
		TM helix 3	103..133	CDD:410630	5/29 (17%)
		TM helix 4	145..165	CDD:410630	3/19 (16%)
		TM helix 5	263..302	CDD:410630	8/38 (21%)
		TM helix 6	349..379	CDD:410630	10/29 (34%)
		TM helix 7	392..417	CDD:410630	5/24 (21%)
srw-42	NP_001023799.1	TM helix 1	36..62	CDD:410630	6/25 (24%)
		7TM_GPCR_Srw	40..356	CDD:402097	87/414 (21%)
		TM helix 2	69..102	CDD:410630	11/35 (31%)
		TM helix 3	120..150	CDD:410630	5/29 (17%)
		TM helix 4	160..180	CDD:410630	7/49 (14%)
		TM helix 5	230..255	CDD:410630	8/40 (20%)
		TM helix 6	274..304	CDD:410630	12/37 (32%)
		TM helix 7	318..343	CDD:410630	5/24 (21%)