DRSC/TRiP Functional Genomics Resources

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Protein Alignment MsR2 and GPR142

DIOPT Version :9

Sequence 1:NP_001261323.1 Gene:MsR2 / 38296 FlyBaseID:FBgn0264002 Length:647 Species:Drosophila melanogaster
Sequence 2:NP_861455.1 Gene:GPR142 / 350383 HGNCID:20088 Length:462 Species:Homo sapiens


Alignment Length:463 Identity:84/463 - (18%)
Similarity:156/463 - (33%) Gaps:163/463 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 VTNMSQPHYCGTGIDDFHTNYKYFHG------------YFSLIVCILGTIANTLNIIVLTR--RE 52
            ||.:..||..|.. .:|.:::.....            |:|:::. ||...:.|..:.|.|  ..
Human   125 VTLLPTPHVSGLS-QEFESHWPEIAERSPCVAGVIPVIYYSVLLG-LGLPVSLLTAVALARLATR 187

  Fly    53 MRSPTNAILTGLAVAD--LAVMLEYIPYTVHDYILSVRLPREEQLSYSWACFIKFHSVFPQVLHT 115
            .|.|:...|..|..:|  :.|::.:..:.:...:|:.::|:         ..::..::.....:.
Human   188 TRRPSYYYLLALTASDIIIQVVIVFAGFLLQGAVLARQVPQ---------AVVRTANILEFAANH 243

  Fly   116 ISIWLTVTLAVWRYIAVSYPQRNRIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLD 180
            .|:|:.:.|.|.||.|:.:|..:|.......|...||......:|...|          |...||
Human   244 ASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIP----------FYWWLD 298

  Fly   181 ANGKTIASVPLSQYILDYNRQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLS 245
            ....|.:...|          |||           :.||                          
Human   299 MWRDTDSPRTL----------DEV-----------LKWA-------------------------- 316

  Fly   246 TGVTTSSSLGERNVTVYKLYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEA 310
                       ..:|||                           .|||....:.:    .|::..
Human   317 -----------HCLTVY---------------------------FIPCGVFLVTN----SAIIHR 339

  Fly   311 KRRRKILACHAANDMQPIVNGKVVIPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIM 375
            .|||      ..:.:||.|.                      ::|.:||.:..||.:...|:..:
Human   340 LRRR------GRSGLQPRVG----------------------KSTAILLGITTLFTLLWAPRVFV 376

  Fly   376 GLLNVLLGDAF-FLQCYLKLSDLMDILALINSSINFILYCSMSRQFRSTFALLFRPRWLDKWLP- 438
            .|.::.:.... ..:.:|.| |:.:::|:::::.||.|||.:|:.||:|...:..    |.:|| 
Human   377 MLYHMYVAPVHRDWRVHLAL-DVANMVAMLHTAANFGLYCFVSKTFRATVRQVIH----DAYLPC 436

  Fly   439 --LSQHDG 444
              .||.:|
Human   437 TLASQPEG 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MsR2NP_001261323.1 7tm_4 28..429 CDD:304433 72/405 (18%)
GPR142NP_861455.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 87..123
7tm_1 176..414 CDD:278431 61/374 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 109 1.000 Inparanoid score I4901
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X861
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.960

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