DRSC/TRiP Functional Genomics Resources

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Protein Alignment MsR2 and Gpr139

DIOPT Version :9

Sequence 1:NP_001261323.1 Gene:MsR2 / 38296 FlyBaseID:FBgn0264002 Length:647 Species:Drosophila melanogaster
Sequence 2:NP_001019412.1 Gene:Gpr139 / 293545 RGDID:1311729 Length:345 Species:Rattus norvegicus


Alignment Length:428 Identity:94/428 - (21%)
Similarity:159/428 - (37%) Gaps:180/428 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 YFSLIVCILGTIANTLNIIVLTR---REMRSPTNAILTGLAVADLAVM--LEYIPYTVHDYILSV 87
            |:|.::| ||..||.|.:|:|::   |..:|..|.:| .||.||:.|:  :.::.:.:.|:||::
  Rat    24 YYSFLLC-LGLPANILTVIILSQLVARRQKSSYNYLL-ALAAADILVLFFIVFVDFLLEDFILTM 86

  Fly    88 RLPR-----EEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIA---------VSYPQRN 138
            ::|.     .|.|.:|             .:|| |||:||.|.|.||||         ||||.|.
  Rat    87 QMPPIPDKIIEVLEFS-------------SIHT-SIWITVPLTVDRYIAVCHPLKYHTVSYPART 137

  Fly   139 RIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNRQDE 203
            |         ..|.:.|:.|.|...|:.:                                    
  Rat   138 R---------KVILSVYITCFLTSIPYYW------------------------------------ 157

  Fly   204 VTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKLYHSA 268
                          |                     |.......::||            ::|..
  Rat   158 --------------W---------------------PNIWTEDYISTS------------MHHVL 175

  Fly   269 LALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPIVNGKV 333
            :.:.       .|.:|     |:||....||:     :::..|.|||                  
  Rat   176 VWIH-------CFTVY-----LVPCSIFFILN-----SIIVYKLRRK------------------ 205

  Fly   334 VIPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVL---LGDAFFLQCYLKLS 395
                  .:.:|  :...|.:||.:|..:..:|.....|:.||.|.::.   :.:.:.:...|   
  Rat   206 ------SNFRL--RGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIML--- 259

  Fly   396 DLMDILALINSSINFILYCSMSRQFR----STFALLFR 429
            |:.::|||:|::|||.|||.:|::||    :|...||:
  Rat   260 DVANMLALLNTAINFFLYCFISKRFRTMAAATLKALFK 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MsR2NP_001261323.1 7tm_4 28..429 CDD:304433 93/426 (22%)
Gpr139NP_001019412.1 7tmA_GPR139 19..288 CDD:320585 91/417 (22%)
TM helix 1 21..45 CDD:320585 10/21 (48%)
TM helix 2 55..77 CDD:320585 7/22 (32%)
TM helix 3 94..116 CDD:320585 11/35 (31%)
TM helix 4 139..155 CDD:320585 4/15 (27%)
TM helix 5 173..196 CDD:320585 8/39 (21%)
TM helix 6 219..241 CDD:320585 6/21 (29%)
TM helix 7 256..281 CDD:320585 12/27 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 104 1.000 Inparanoid score I4851
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D343117at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X861
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.970

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