Protein Alignment MsR2 and dmsr-6

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_497004.1
• Gene: dmsr-6 / 190297
• WormBaseID: WBGene00013222
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 122/481 - (25%)
• Similarity: 190/481 - (39%)
• Gaps: 135/481 - (28%)

  Fly    18 FHTNYKYFHGYFSLIVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTVH 81
            |...|...|.:.|.|:|:||..||.::|.||||..|| |..:.:|..:|::|:..|..|:.|...
 Worm    26 FRYLYSNVHPFLSFILCVLGLAANAIHITVLTRPRMRHSSVHTVLVCIAISDMGTMTSYLMYISR 90

  Fly    82 DYILSVRLPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAVSYPQRNRIWCGMRT 146
            ...||    .:|..||.||.|:|.|::....||.|:::|.|.:|..|..|:.
 Worm    91 FEFLS----DKEGYSYFWALFLKCHAMLSIALHAITLYLVVLMAFIRLSAMK------------- 138

  Fly   147 TLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNRQDEVTMQVMSS 211
                         |..|.|                              ||:.|
 Worm   139 -------------LTTSRW------------------------------LDHTR----------- 149

  Fly   212 TTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKLYH------SALA 270
                   |:.|    ...::|......:| |.|:..:..::    |.||:..:|:      |.|.
 Worm   150 -------ALTS----AIFIALFVFIMCVP-TLLAHQIDETT----RGVTMNGMYYKYSVGFSTLM 198

  Fly   271 LRDR-QFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPIVNGKVV 334
            :::. ........:..:.:|.|||..|...::.||..|.|...:||||
 Worm   199 MQNGCSLMKGNLWLTGIFLKAIPCLLLLTFTIALINRLRENNEKRKIL----------------- 246

  Fly   335 IPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLGDAFFLQCYLKLSDLMD 399
                   .|....:|:.|.||.|||.::.:||.||.|||||.:||.|....|....||.|:|::|
 Worm   247 -------IKEERAKKRGDFTTYMLLLMVTVFLFTELPQGIMAILNALFTTQFHQMVYLNLADVLD 304

  Fly   400 ILALINSSINFILYCSMSRQFRST-FALLFRPRWLDKWLPLSQHDGEGRVGGSGGLGGYGGYGRQ 463
            :|:|||..:.|::|...|.::|.| |:|          |||::....|.....|.|..:...|.:
 Worm   305 LLSLINCYVAFLVYSFTSSRYRQTLFSL----------LPLTKISYSGISTRQGTLKSHQHPGAK 359

  Fly   464 RLLHTD-----AVSKSMAIDLGLTTQ 484
            .|:...     |.::|..:|....|:
 Worm   360 TLVQRANSVEVASARSPLVDKAAITR 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	106/408 (26%)
		TM helix 1	25..51	CDD:410630	12/25 (48%)
		TM helix 2	57..82	CDD:410630	6/24 (25%)
		TM helix 3	103..133	CDD:410630	10/29 (34%)
		TM helix 4	145..165	CDD:410630	2/19 (11%)
		TM helix 5	263..302	CDD:410630	8/45 (18%)
		TM helix 6	349..379	CDD:410630	16/29 (55%)
		TM helix 7	392..417	CDD:410630	10/24 (42%)
dmsr-6	NP_497004.1	7tmA_FMRFamide_R-like	33..329	CDD:410630	105/406 (26%)
		TM helix 1	33..59	CDD:410630	12/25 (48%)
		TM helix 2	66..91	CDD:410630	6/24 (25%)
		TM helix 3	108..138	CDD:410630	10/29 (34%)
		TM helix 4	148..168	CDD:410630	5/42 (12%)
		TM helix 5	206..231	CDD:410630	5/24 (21%)
		TM helix 6	254..284	CDD:410630	16/29 (55%)
		TM helix 7	297..322	CDD:410630	10/24 (42%)