Protein Alignment MsR2 and dmsr-3

DIOPT Version :9

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_496818.1
• Gene: dmsr-3 / 190021
• WormBaseID: WBGene00012993
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 424
• Identity: 87/424 - (20%)
• Similarity: 171/424 - (40%)
• Gaps: 125/424 - (29%)

  Fly    13 TGIDDFHTNY-KYFHGYFSLIVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYI 76
            |..:.|...| :..|....|::||.|.:.:.|.|..|:  .|.:|||..|..::.:.||:.:.::
 Worm    11 TVFETFLLEYGRIIHPPMVLLLCISGALGHMLTITTLS--SMLNPTNMFLISMSCSQLALCINFL 73

  Fly    77 PYTVHDYILSVRLPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAVSYPQRNRIW 141
             |:.....:|.:|.:....||..|..:.|......::|..:::..|.|::.|:.:::.
 Worm    74 -YSTFFKFMSDQLCQPFFFSYYLATTMHFSVTVSVLVHMSAVFHVVALSLIRFFSLAQ------- 130

  Fly   142 CGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNRQDEVTM 206
                                                                             
 Worm   131 ----------------------------------------------------------------- 130

  Fly   207 QVMSSTTPDVSWAIPSDSANGTAVSLLSLTTV---IPL--TTLSTGVTTSSSLGE-----RNVTV 261
              :||...:|.|.....|.  .|:.::.::.:   |||  |:..|.|:.:....|     ||...
 Worm   131 --LSSVNSNVQWFTWQKSR--VAIIMIYVSVIFLCIPLHFTSQVTEVSENEGCAERYPALRNKVA 191

  Fly   262 YKL-YHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDM 325
            |:| |..::.|     ||..|.::.::.|::|...|.|::.    .:|:..::.::|:...::
 Worm   192 YQLSYTQSIWL-----RNLNFWLFYLVAKVVPSIILCIMTC----LILDQLKKIQVLSARFSS-- 245

  Fly   326 QPIVNGKVVIPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLGDAFFLQC 390
                               :|::||..|||.|:||:::||::.|.|||::.:|:.:..    ::.
 Worm   246 -------------------VERDKQHSRTTNMILAIMILFIIVELPQGVLAVLSTVTS----VKL 287

  Fly   391 YLKLSDLMDILALINSSINFILYCSMSRQFRSTF 424
            ..:|.||.::..|:.|.|.|.|.|||:.:.||.|
 Worm   288 IYELGDLTELFTLLTSIIIFTLLCSMNGKIRSAF 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tm_4	28..429	CDD:304433	83/408 (20%)
dmsr-3	NP_496818.1	7tm_GPCRs	23..321	CDD:391938	83/410 (20%)
		TM helix 1	24..48	CDD:341315	7/23 (30%)
		TM helix 2	54..78	CDD:341315	6/24 (25%)
		TM helix 3	99..129	CDD:341315	5/29 (17%)
		TM helix 4	144..164	CDD:341315	3/21 (14%)
		TM helix 5	203..228	CDD:341315	7/28 (25%)
		TM helix 6	250..280	CDD:341315	14/29 (48%)
		TM helix 7	291..314	CDD:341315	10/22 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46273
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870