Protein Alignment MsR2 and dmsr-5

DIOPT Version :9

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_499413.1
• Gene: dmsr-5 / 190009
• WormBaseID: WBGene00012962
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 429
• Identity: 101/429 - (23%)
• Similarity: 174/429 - (40%)
• Gaps: 106/429 - (24%)

  Fly    18 FHTNYKYFHGYFSLIVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYI----- 76
            |:..|...|.|..|.||..|.:.|:|:..||||:.|| ...||:|..:::.|:..|..|.
 Worm    26 FNQVYTVLHRYLCLFVCFFGVLLNSLHFYVLTRKAMRVYIINALLCAMSICDIITMTSYFIYILR 90

  Fly    77 ------PYTVHDYILSVRLPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAVSYP 135
                  |.|:..|            ||.|..|:..|......|||.|::|:|.:|..|:.|:...
 Worm    91 FRIFDTPSTIIGY------------SYPWLIFLITHVTSSIALHTTSLYLSVIMAYIRWTALDRL 143

  Fly   136 QRNRIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNR 200
            ....|..|....:: |.||.:|.|:.:.     ...:.|.             ||::: :|..|.
 Worm   144 DAKWINHGALKQIL-IFTALIVSVISIP-----TVMVHKI-------------VPVTE-VLGMNE 188

  Fly   201 QDEVTMQVMSSTTPDVSWAIPSDSA--NGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYK 263
            .|     ::.....|..:.:..|..  ||.|:..::|
 Worm   189 TD-----LLEGAKFDGLYTVQLDETKINGCALFRVNL---------------------------- 220

  Fly   264 LYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPI 328
                              .|..::.|.:||..:...::.||..|::...:||||......:::..
 Worm   221 ------------------WITGIMFKALPCLLILWFTIALIYKLVQMSEKRKILRGEKRENVEFQ 267

  Fly   329 VNGKVVIPT-------QPKSCKLLE--KEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLGD 384
            :......||       .|:..|:.:  :....||||.||:.:|::||.||.|||::.:|:.:...
 Worm   268 LLATSATPTTTTRNEASPRLRKVSQCSRNVSIDRTTLMLIIMLVVFLCTEMPQGLLSILSAIYPT 332

  Fly   385 AFFLQCYLKLSDLMDILALINSSINFILYCSMSRQFRST 423
            ......|:.:.:::|:::|||...:||:||.||..:|:|
 Worm   333 HVHTMIYVNVGEVLDLMSLINCLTSFIVYCVMSTTYRAT 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tm_4	28..429	CDD:304433	98/419 (23%)
dmsr-5	NP_499413.1	7tmA_FMRFamide_R-like	32..372	CDD:320109	99/423 (23%)
		TM helix 1	34..58	CDD:320109	10/23 (43%)
		TM helix 2	67..89	CDD:320109	6/21 (29%)
		TM helix 3	112..134	CDD:320109	7/21 (33%)
		TM helix 4	155..171	CDD:320109	5/21 (24%)
		TM helix 5	217..240	CDD:320109	5/68 (7%)
		TM helix 6	300..325	CDD:320109	14/24 (58%)
		TM helix 7	340..365	CDD:320109	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45310
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109662
Panther	1	1.100	-	-	O	PTHR46273
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.780