DRSC/TRiP Functional Genomics Resources

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Protein Alignment MsR2 and srw-54

DIOPT Version :9

Sequence 1:NP_001261323.1 Gene:MsR2 / 38296 FlyBaseID:FBgn0264002 Length:647 Species:Drosophila melanogaster
Sequence 2:NP_507202.1 Gene:srw-54 / 189573 WormBaseID:WBGene00005801 Length:351 Species:Caenorhabditis elegans


Alignment Length:412 Identity:82/412 - (19%)
Similarity:154/412 - (37%) Gaps:138/412 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 YFSLIVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLEYIPYTVHDYILSVR--- 88
            ||:..:.::|.|||..::|||.|:.||:.| |..:.|:|:.:...|:.|:...:..|....:   
 Worm    39 YFNFSISVVGVIANIFHLIVLGRKSMRALTVNTFMMGIAICEFVRMMCYVIMRIPKYYRKYQKFK 103

  Fly    89 -----LPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAVSYPQRNRIWCGMRTTL 148
                 :|.:   ||...|.:...|:....:....|.:.|.:||.|.:::.||..::|        
 Worm   104 FGRFCVPPD---SYLTICIVNNSSILFNSIQDPLISIAVAMAVLRTVSLKYPMSSKI-------- 157

  Fly   149 ITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNRQDEVTMQVMSSTT 213
                             |.::..|               ::|.  :.||:: |.:||::    :.
 Worm   158 -----------------LLIIRGI---------------TIPF--WALDFS-QTQVTVE----SD 183

  Fly   214 PDVSWAIPSDS---ANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKLYHS-ALALRDR 274
            |   |.:|.|.   |.|                                   :.|.| ..:|:::
 Worm   184 P---WRLPDDCKHFAEG-----------------------------------RFYFSTTTSLQNQ 210

  Fly   275 QFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKI--LACHAANDMQPIVNGKVVIPT 337
            .|   ..||..:|.|||....|.|.::.||.   :.|.|.|:  :...|:|              
 Worm   211 GF---VLLIQGILFKLILSLVLPIATLILIH---DIKMRNKVSSVGSSASN-------------- 255

  Fly   338 QPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLN-VLLGDAFFLQCYLKLSDLMDIL 401
                          ||:|.:::.:.:.|::...|||::.|:. ....|...:.....|::....:
 Worm   256 --------------DRSTNLVVFMTISFIIALAPQGVLYLIKFTYKNDEGVVSTIETLNNFHAFV 306

  Fly   402 ALINSSINFILYCSMSRQFRST 423
            .|.|.:|:.|:...:|..:|.|
 Worm   307 PLANGTIHIIINFFISSMYRRT 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MsR2NP_001261323.1 7tm_4 28..429 CDD:304433 82/412 (20%)
srw-54NP_507202.1 7TM_GPCR_Srw 39..336 CDD:370978 82/412 (20%)
TM helix 1 39..62 CDD:341315 9/22 (41%)
TM helix 2 69..94 CDD:341315 5/24 (21%)
TM helix 3 120..150 CDD:341315 6/29 (21%)
TM helix 5 201..235 CDD:341315 11/36 (31%)
TM helix 6 253..283 CDD:341315 10/57 (18%)
TM helix 7 294..322 CDD:341315 5/27 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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