Protein Alignment MsR2 and dmsr-2

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_490992.2
• Gene: dmsr-2 / 189527
• WormBaseID: WBGene00021275
• Length: 407
• Species: Caenorhabditis elegans
• Alignment Length: 424
• Identity: 104/424 - (24%)
• Similarity: 170/424 - (40%)
• Gaps: 115/424 - (27%)

  Fly    18 FHTNYKYFHGYFSLIVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTVH 81
            |..::..||.|..:.:|::|..||...::||.|..|| ||.|..|..:||.|.::|..|:.|.
 Worm    25 FTASFTMFHNYIYVFLCVIGVFANISIVVVLLRPAMRKSPFNLFLVVIAVCDASLMATYLTYK-- 87

  Fly    82 DYILSVRLPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAV--------SYPQRN 138
                .|.|......|:.||.:.||:::|...:|:.|:||||.:|:.|::.:        ..||.|
 Worm    88 ----HVELCHPWYFSFPWAIYTKFYAIFSVFVHSCSLWLTVNMAILRFLVLYRGSRSETRIPQCN 148

  Fly   139 RIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVP----LSQYILDYN 199
            .........::..|.|.:.|:.:             |:......|: :.:||    ..:|..|:.
 Worm   149 GFGAAFVAIVLAFAIACIGCLPI-------------FIRYRIIEGE-VGAVPDLCLEGKYSTDWQ 199

  Fly   200 RQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKL 264
            ..|.:....:|.   .:.|....:..|
 Worm   200 PNDMIQFYGLSQ---PLWWNCDWERIN-------------------------------------- 223

  Fly   265 YHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPIV 329
                            :.:.::::|||||..|||....|:..|:||:.||..| |....
 Worm   224 ----------------YWMAALILKLIPCLLLTIFMTLLVRMLIEARERRSRL-CGGMG------ 265

  Fly   330 NGKVVIPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLGDAFFLQCYLKL 394
            ||                ..|.:|||.||..::.:||:||.|||::...........||.  |::
 Worm   266 NG----------------NSQAERTTAMLTGIVAIFLITELPQGVLTFAAGANPRLTFLT--LQM 312

  Fly   395 SDLMDILALINSSINFILYCSMSRQFRSTFALLF 428
            :::.|:|:||||::||:|...||..||..|...|
 Worm   313 NNVFDLLSLINSAVNFVLCALMSHVFRREFLQTF 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	101/412 (25%)
		TM helix 1	25..51	CDD:410630	9/25 (36%)
		TM helix 2	57..82	CDD:410630	8/24 (33%)
		TM helix 3	103..133	CDD:410630	11/37 (30%)
		TM helix 4	145..165	CDD:410630	3/19 (16%)
		TM helix 5	263..302	CDD:410630	8/38 (21%)
		TM helix 6	349..379	CDD:410630	13/29 (45%)
		TM helix 7	392..417	CDD:410630	10/24 (42%)
dmsr-2	NP_490992.2	7tmA_FMRFamide_R-like	32..342	CDD:410630	101/411 (25%)
		TM helix 1	32..58	CDD:410630	9/25 (36%)
		TM helix 2	64..94	CDD:410630	11/35 (31%)
		TM helix 3	105..135	CDD:410630	11/29 (38%)
		TM helix 4	151..171	CDD:410630	3/19 (16%)
		TM helix 5	220..245	CDD:410630	9/78 (12%)
		TM helix 6	272..299	CDD:410630	12/26 (46%)
		TM helix 7	311..335	CDD:410630	9/23 (39%)