Protein Alignment MsR2 and srw-79

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001364795.1
• Gene: srw-79 / 188412
• WormBaseID: WBGene00005826
• Length: 349
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 84/443 - (18%)
• Similarity: 159/443 - (35%)
• Gaps: 138/443 - (31%)

  Fly    14 GIDDFHTNYKYFHGYFSLIVCI------LGTIANTLNIIVLTRREMR-SPTNAILTGLAVAD--- 68
            |:|  :..|:.|....|.|..:      .|.|.|..:|.:|||..|| |.||:::.|:|:.|
 Worm     4 GLD--YPVYENFKNIVSEIDVVQNYASTAGVIMNIPHIFILTRSSMRTSSTNSLMIGIAICDILY 66

  Fly    69 LAVMLE-YIPYTVHDYILSVRLPREEQLSYSWACFIKFHSVFPQVLHTISIWLTVTLAVWRYIAV 132
            |:::.| :|........|.:.:.     ||::............::...|.||...||:.|||.:
 Worm    67 LSILAELWIRNAYFSDFLCINVG-----SYAYIVSAWILECLRDLIEKASFWLGFMLAMTRYIIM 126

  Fly   133 SYPQRNRIWCGMRTTLITIATAYVVCVLV------VSPWLYLVTAIAKFLETLDANGKTIASVPL 191
            ..       .|....|...::.|::..::      :|.|.|
 Worm   127 KS-------SGRADKLARPSSGYLITFIISVISAALSGWYY------------------------ 160

  Fly   192 SQYILDYNRQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGE 256
            .:|.|:.::...:.....:...|.|
 Worm   161 GRYYLEKDQNLWIMWDECAGYRPKV---------------------------------------- 185

  Fly   257 RNVTVYKLYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHA 321
            :.:..:      |.:.|....:.:..|.:.:.:.:..|...|:.|.|   ::|.:|..|..|
 Worm   186 KGIRYF------LVMDDAAIHSRSHTIINAISRTLISFLYPIIGVLL---MVEIRRSAKFAA--- 238

  Fly   322 ANDMQPIVNGKVVIPTQPKSCKLLEKEKQ-TDR--TTRMLLAVLLLFLVTEFPQGIMGLLNV--L 381
                                 |.|:.||. |:|  .:||:|.:.:::.:...|.|.:..:||  :
 Worm   239 ---------------------KKLKSEKSATERYHASRMILVMTVMYFLASAPIGALDFINVSEI 282

  Fly   382 LGDAFFLQCYLKLSD-LMDILALINSSINFILYCSMSRQFRSTFALLFRPRWL 433
            :.::.||:..|..|. ||..:..:||:.:.|:..|||..:|:|..:    .|:
 Worm   283 VTESSFLRLSLDHSAYLMSAIFCLNSASHCIINLSMSSAYRNTIKM----SWM 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	79/422 (19%)
		TM helix 1	25..51	CDD:410630	9/31 (29%)
		TM helix 2	57..82	CDD:410630	8/28 (29%)
		TM helix 3	103..133	CDD:410630	8/29 (28%)
		TM helix 4	145..165	CDD:410630	3/25 (12%)
		TM helix 5	263..302	CDD:410630	5/38 (13%)
		TM helix 6	349..379	CDD:410630	8/32 (25%)
		TM helix 7	392..417	CDD:410630	8/25 (32%)
srw-79	NP_001364795.1	7TM_GPCR_Srw	23..328	CDD:402097	77/413 (19%)
		TM helix 2	53..75	CDD:410628	6/21 (29%)
		TM helix 3	98..120	CDD:410628	4/21 (19%)
		TM helix 4	143..159	CDD:410628	1/15 (7%)
		TM helix 5	193..224	CDD:410628	4/30 (13%)
		TM helix 6	254..279	CDD:410628	5/24 (21%)
		TM helix 7	294..319	CDD:410628	7/24 (29%)