Protein Alignment MsR2 and egl-6

DIOPT Version :9

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001257033.1
• Gene: egl-6 / 183513
• WormBaseID: WBGene00001175
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 461
• Identity: 123/461 - (26%)
• Similarity: 199/461 - (43%)
• Gaps: 119/461 - (25%)

  Fly     3 TNMSQPHYCGTGIDD--FHTNYKYFHGYFSLIVCILGTIANTLNIIVLTRREMRSPTNAILTGLA 65
            ||:|     ...|.|  |...|...|...|:.:||.|..:|..|||||||:.||:|.|.:||||:
 Worm    16 TNVS-----SRAITDKSFLQYYDEIHIPLSISICIFGAASNVFNIIVLTRKRMRTPINILLTGLS 75

  Fly    66 VADLAVMLEYIPYTVHDYILSVRLPREEQLSYSWA-CFIK---FHSVFPQVLHTISIWLTVTLAV 126
            :|...:...|..|.:.:|.      |.:.:...|: .|.:   |:.....|.|||:...|:.:||
 Worm    76 IAQWLLATNYFLYLLLEYY------RYQCVQLLWSEAFTRYRFFNVNLNTVFHTIAFTTTIVVAV 134

  Fly   127 WRYIAVSYP-QRNRIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVP 190
            :||.|:.:| |.||.....:..:......:::..::..| |:.::.:           |.:|...
 Worm   135 FRYCALKFPIQANRFIYKCQPAIAANVIIWIIIPIISLP-LFFISEV-----------KIVARDH 187

  Fly   191 LSQYILDYNRQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLG 255
            ::     |:.|.|     |.....|:|:   .:|               ||..
 Worm   188 VA-----YDLQCE-----MEGPLYDLSY---QES---------------PLLV------------ 212

  Fly   256 ERNVTVYKLYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACH 320
                                  :|.|..:.::.||:|...|:||.:.||.:|...:||||
 Worm   213 ----------------------SAVFWAFGIVFKLLPSLILSILLIALIRSLKSVERRRK----- 250

  Fly   321 AANDMQPIVNGKVVIPTQPKSCKLLEKEKQT--DRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLG 383
               :.:......:...::.|:     |.|.|  .||||||:.:|||.::.|.|.||:.|...:.|
 Worm   251 ---NWKRTQGANICTNSERKA-----KRKLTTRPRTTRMLVIILLLCVMVELPMGILNLCVAIYG 307

  Fly   384 DAFFLQCYLKLSDLMDILALINSSINFILYCSMSRQFRSTFALLFRPRWLDK---------WLPL 439
            :.|..:.|..:.:||::|.|:.||::|:|||:||.::.|||..||.| |..|         |  .
 Worm   308 EEFGNRYYDPVGNLMEMLTLLYSSVSFVLYCTMSNEYLSTFRALFFP-WTRKNSLRGTRRSW--N 369

  Fly   440 SQHDGE 445
            .:||.|
 Worm   370 HRHDDE 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tm_4	28..429	CDD:304433	107/407 (26%)
egl-6	NP_001257033.1	7tmA_FMRFamide_R-like	35..348	CDD:320109	105/405 (26%)
		TM helix 1	35..61	CDD:320109	12/25 (48%)
		TM helix 2	67..92	CDD:320109	8/24 (33%)
		TM helix 3	111..141	CDD:320109	11/29 (38%)
		TM helix 4	154..174	CDD:320109	1/20 (5%)
		TM helix 5	212..237	CDD:320109	8/58 (14%)
		TM helix 6	273..303	CDD:320109	15/29 (52%)
		TM helix 7	316..341	CDD:320109	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46273
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010