Protein Alignment MsR2 and frpr-1

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_509368.3
• Gene: frpr-1 / 182105
• WormBaseID: WBGene00015323
• Length: 378
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 85/451 - (18%)
• Similarity: 159/451 - (35%)
• Gaps: 162/451 - (35%)

  Fly    11 CGTGIDDFHT-----NYKYFH----GYFSLIVCILGTIANTLNIIVLTRREMRSPTNAILTGLAV 66
            ||...|...|     .|:.|:    |....::..||.|.|.|:....:||||.|..|..|..||.
 Worm    26 CGYCYDFVETRQVVKEYEQFNLVVIGLMLPLIGCLGLIGNALSAFTYSRREMISSLNVYLFALAC 90

  Fly    67 ADLAVMLEYIPYTVHDYILSVRLPREEQLSYSWACFIKFHSVFPQVL--HTISIWLTVTLAVWRY 129
            :|:.::|.    ....:.|.....|.|..:|.:|  :....:||..|  .|:|:::||..|....
 Worm    91 SDIVIILT----AFFLFFLENMRKRSEWATYYFA--VLSPVMFPLGLTAQTMSVFITVASAFDCL 149

  Fly   130 IAVSYPQRNRI-WCGMRTTLIT---------------IATAYVVCVLVVSPWLYLVTAIAKFLET 178
            :.|:..::.:. :|.:.|:::.               |...:::.:...||.:|.:
 Worm   150 VLVAASEKFKSKFCSVNTSILVGNFNDFKNVIVCLKIIVKIFLLGIFYNSPHMYEI--------- 205

  Fly   179 LDANGKTIASVPLSQYILDYNRQDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTT 243
                           |::|                   .|:...::|:         ..|.| |.
 Worm   206 ---------------YVID-------------------CWSTMYNTAS---------KDVCP-TA 226

  Fly   244 LSTGVTTSSSLGERNVTVYKLYHSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALL 308
            |.:.|.        .|.:|.:|                 :|::::.:.|...|.:::.    |::
 Worm   227 LRSNVD--------YVRIYYVY-----------------MYTIVMAVGPVLLLIVINT----AIV 262

  Fly   309 EAKRRRKILACHAANDMQPIVNGKVVIPTQPKSCKLLEKEKQTDRTTRMLLAVL-----LLFLVT 368
            .:.||                      .:.|.|        ::|..|.:|:..|     :|.|..
 Worm   263 ISMRR----------------------SSSPNS--------ESDIITLVLVVCLFISCNVLPLTV 297

  Fly   369 EFPQGIMGLLNVLLGDAFFLQCYLKLSDLMDILALINSSINFILYCSMSRQFRSTFALLFR 429
            .|.:.:.|::|..            |.||.:::.::|||.||::|.:....||.|.....|
 Worm   298 NFLELLFGIINSY------------LIDLSNLMVVVNSSCNFLIYYTFGSNFRRTLRYYVR 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	78/426 (18%)
		TM helix 1	25..51	CDD:410630	7/29 (24%)
		TM helix 2	57..82	CDD:410630	6/24 (25%)
		TM helix 3	103..133	CDD:410630	8/31 (26%)
		TM helix 4	145..165	CDD:410630	3/34 (9%)
		TM helix 5	263..302	CDD:410630	4/38 (11%)
		TM helix 6	349..379	CDD:410630	8/34 (24%)
		TM helix 7	392..417	CDD:410630	9/24 (38%)
frpr-1	NP_509368.3	7tmA_FMRFamide_R-like	48..341	CDD:410630	77/422 (18%)
		TM helix 1	49..75	CDD:410630	6/25 (24%)
		TM helix 2	81..106	CDD:410630	6/28 (21%)
		TM helix 3	123..153	CDD:410630	8/29 (28%)
		TM helix 4	166..201	CDD:410630	3/34 (9%)
		TM helix 5	235..260	CDD:410630	5/45 (11%)
		TM helix 6	271..301	CDD:410630	9/37 (24%)
		TM helix 7	309..334	CDD:410630	9/36 (25%)