Protein Alignment MsR2 and frpr-17

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_510400.2
• Gene: frpr-17 / 181541
• WormBaseID: WBGene00011765
• Length: 403
• Species: Caenorhabditis elegans
• Alignment Length: 450
• Identity: 90/450 - (20%)
• Similarity: 153/450 - (34%)
• Gaps: 157/450 - (34%)

  Fly    18 FHTNYKYFHGYFSLIVC--------ILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLE 74
            :|.:.::.:..|::||.        :.|.:.|.::..|.:|.|||..||..|..||.:|..|:|.
 Worm    58 YHGSKEWDYIRFNIIVIGIILPIVGVFGIVGNAISAFVYSRPEMRCSTNLYLFSLACSDTGVVLT 122

  Fly    75 YIPYTVHDYILSVRLPREEQLSYSWACFIKFHSVFP--QVLHTISIWLTVTLAVWRYIAVSYPQR 137
            .|      ::.|:...|...|:.:.........|:|  .:..|.|::.||...|..::.|..|::
 Worm   123 GI------FLFSLETFRPFSLTVARISGQLSAIVYPMGMIAQTCSVYFTVCAGVDCFVQVCLPEK 181

  Fly   138 NRIWCGMRTTLITIATAYVVCVLVVSPWLYLVTAIAKFLETLDANGKTIASVP--LSQYILDYNR 200
            .|.....:.|:..:||    ||::.|                     .:.:||  ...:::|...
 Worm   182 VRRAFSRKETVHFLAT----CVVIFS---------------------VLYNVPHFFEGFVIDCYH 221

  Fly   201 QDEVTMQVMSSTTPDVSWAIPSDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKLY 265
            |:   :..||.                         .|.|.|.         ...|...::|..|
 Worm   222 QE---LGGMSK-------------------------EVCPATL---------RYNEMYQSIYYKY 249

  Fly   266 HSALALRDRQFRNATFLIYSVLIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPIVN 330
                             :|::.:.:.|.|.|.||:..:||.        .:....|:|
 Worm   250 -----------------MYAIFLAVGPLFTLIILNTLIIGF--------SVFGSSASN------- 282

  Fly   331 GKVVIPTQPKSCKLLEKEKQTDRTTRMLLAVLLLFLVTEFPQGIMGLLNVLLGDAFFLQCYLK-- 393
                                .|.|..::|.|||......    |..::|:       .:.||.
 Worm   283 --------------------MDDTMSLILVVLLFICCNT----IALVINI-------FESYLSET 316

  Fly   394 -------LSDLMDILALINSSINFILYCSMSRQFRSTFALLFRPRWLDKWLPLSQHDGEG 446
                   :.||.:.|.:.|||.|.|:|...||.|..|....|..|     .|::.:||.|
 Worm   317 LGSKINYIVDLSNFLVVFNSSFNIIIYIKYSRPFADTLFSYFCNR-----KPITDNDGPG 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	82/420 (20%)
		TM helix 1	25..51	CDD:410630	6/33 (18%)
		TM helix 2	57..82	CDD:410630	9/24 (38%)
		TM helix 3	103..133	CDD:410630	7/31 (23%)
		TM helix 4	145..165	CDD:410630	6/19 (32%)
		TM helix 5	263..302	CDD:410630	7/38 (18%)
		TM helix 6	349..379	CDD:410630	7/29 (24%)
		TM helix 7	392..417	CDD:410630	10/33 (30%)
frpr-17	NP_510400.2	7tmA_FMRFamide_R-like	81..354	CDD:410630	79/403 (20%)
		TM helix 2	105..130	CDD:410630	10/30 (33%)
		TM helix 3	147..177	CDD:410630	7/29 (24%)
		TM helix 4	189..210	CDD:410630	7/45 (16%)
		TM helix 5	244..269	CDD:410630	8/41 (20%)
		TM helix 6	280..310	CDD:410630	10/67 (15%)
		TM helix 7	322..347	CDD:410630	9/24 (38%)