Protein Alignment MsR2 and frpr-18

DIOPT Version :10

• Sequence 1: NP_001261323.1
• Gene: MsR2 / 38296
• FlyBaseID: FBgn0264002
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_504746.1
• Gene: frpr-18 / 179076
• WormBaseID: WBGene00020586
• Length: 432
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 83/419 - (19%)
• Similarity: 157/419 - (37%)
• Gaps: 146/419 - (34%)

  Fly    31 LIVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLEYIPYTVHDYILSVRL-PREE 93
            |::.::|...|:|:.|:.:|..|||.: |.:|..|:..|.:::...||..|   |.::.| ..:.
 Worm    12 LVIVLVGIFGNSLSFILFSRPHMRSSSVNVLLCALSFFDFSLLTLSIPIFV---IPNLDLWANDL 73

  Fly    94 QLSYSWACFIKFHSVFP--QVLHTISIWLTVTLAVWRYIAVSYPQRNRIWCGMRTTLITIATAYV 156
            .||...|..:|.  ::|  .::.|.|:::.|.:.:.|::||..|.:.|:||..|      .:...
 Worm    74 SLSTYMAYILKL--IYPINLMMQTCSVYIMVMITLERWVAVCRPLQVRVWCTPR------KSRNA 130

  Fly   157 VCVLVVSPWLYLVTAIAKFLETLDANGKTIASVPLSQYILDYNRQDEVTMQVMSSTTPDVSWAIP 221
            :.|::||.:||   ...:|.|              .:::
 Worm   131 ILVIIVSAFLY---NFVRFFE--------------YRFV-------------------------- 152

  Fly   222 SDSANGTAVSLLSLTTVIPLTTLSTGVTTSSSLGERNVTVYKLYHSALALRDRQFRNATFLIYSV 286
                                      ||.|.:|.|:            .|||.......::.|..
 Worm   153 --------------------------VTESGALYEK------------WLRDPGKHRWYYVGYYT 179

  Fly   287 LIKLIPCFALTILSVRLIGALLEAKRRRKILACHAANDMQPIVNGKVVIPTQPKSCKL------L 345
            ::.::..|.:..                         .:....||.|::    ..|||      |
 Worm   180 ILYIVTHFLVPF-------------------------SVMAFANGHVIV----AMCKLSKTRQML 215

  Fly   346 EKEKQTDR-TTRMLLAVLLLFLVTEFPQGIMGLLNVLLGDAFFLQCYLK---------LSDLMDI 400
            .:::|.:: ||.|||.|..:|.:.   ..:..||||  .::.|...:..         |:||.::
 Worm   216 TRQQQREQSTTVMLLIVTFVFAIC---NTLPFLLNV--SESIFPTLFQDESTRGLAYWLNDLSNL 275

  Fly   401 LALINSSINFILYCSMSRQFRSTFALLFR 429
            |.::||...||:|.:.|.::|.|...:.:
 Worm   276 LVVLNSGTTFIIYFTFSEKYRQTLVFILK 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR2	NP_001261323.1	7tmA_FMRFamide_R-like	24..424	CDD:410630	82/412 (20%)
		TM helix 1	25..51	CDD:410630	5/19 (26%)
		TM helix 2	57..82	CDD:410630	7/25 (28%)
		TM helix 3	103..133	CDD:410630	7/31 (23%)
		TM helix 4	145..165	CDD:410630	4/19 (21%)
		TM helix 5	263..302	CDD:410630	5/38 (13%)
		TM helix 6	349..379	CDD:410630	9/30 (30%)
		TM helix 7	392..417	CDD:410630	9/33 (27%)
frpr-18	NP_504746.1	7tmA_FMRFamide_R-like	6..299	CDD:410630	82/412 (20%)
		TM helix 1	6..32	CDD:410630	5/19 (26%)
		TM helix 2	39..64	CDD:410630	7/27 (26%)
		TM helix 3	83..113	CDD:410630	7/31 (23%)
		TM helix 4	125..145	CDD:410630	6/28 (21%)
		TM helix 5	175..200	CDD:410630	3/49 (6%)
		TM helix 6	220..250	CDD:410630	12/34 (35%)
		TM helix 7	267..292	CDD:410630	9/24 (38%)