DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oxt and GCNT3

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	NP_004742.1	Gene:	GCNT3 / 9245	HGNCID:	4205	Length:	438	Species:	Homo sapiens

Alignment Length:	338	Identity:	85/338 - (25%)
Similarity:	150/338 - (44%)	Gaps:	53/338 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 SEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLE-LESKFPNIRL 305
            |:|.....||:.:.::.: :....|||:|:|||:::|.:||||:....:::.:: :.|.|||:.:
Human   125 SKEEVEFPIAYSMVIHEK-IENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAIISCFPNVFI 188

  Fly   306 ARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVKTLDKLVDFLSANPGRNFVK 370
            |.|....::...|.:...|.||||||||:..|.:.:|...:|||:|:..::|..|....|||.::
Human   189 ASKLVRVVYASWSRVQADLNCMEDLLQSSVPWKYFLNTCGTDFPIKSNAEMVQALKMLNGRNSME 253

  Fly   371 G-----HGRETQKFIQKQGLDKTFVECDT-HMWRIGDRKLPAGIQVDGGSDWVALSRPFVGYV-T 428
            .     |.....|:..:       |..|| |:........|..:.:..|:.::..||.||.:| .
Human   254 SEVPPKHKETRWKYHFE-------VVRDTLHLTNKKKDPPPYNLTMFTGNAYIVASRDFVQHVLK 311

  Fly   429 HPREDDELLQALLKLFRHTLLPAESFFHTVLR----------NTKHCTSYVDNNLHVTNWKRKQG 483
            :|:.     |.|::..:.|..|.|..:.|:.|          :.|:..|.:.:...:..|:..:|
Human   312 NPKS-----QQLIEWVKDTYSPDEHLWATLQRARWMPGSVPNHPKYDISDMTSIARLVKWQGHEG 371

  Fly   484 --------CKCQYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWL 540
                    ..|...|....|.....|.   :|     ..|.....|.||:|.::...|..|||:|
Human   372 DIDKGAPYAPCSGIHQRAICVYGAGDL---NW-----MLQNHHLLANKFDPKVDDNALQCLEEYL 428

  Fly   541 YGPYTSEYANLHG 553
                  .|..::|
Human   429 ------RYKAIYG 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068
		Branch	250..503	CDD:280621	70/278 (25%)
		Xylo_C	537..710	CDD:289306	5/17 (29%)
GCNT3	NP_004742.1	Branch	133..401	CDD:308216	71/288 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156651
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0799
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740