DRSC/TRiP Functional Genomics Resources

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Protein Alignment oxt and Kremen1

DIOPT Version :9

Sequence 1:NP_647705.1 Gene:oxt / 38288 FlyBaseID:FBgn0015360 Length:876 Species:Drosophila melanogaster
Sequence 2:NP_115772.2 Gene:Kremen1 / 84035 MGIID:1933988 Length:473 Species:Mus musculus


Alignment Length:273 Identity:66/273 - (24%)
Similarity:98/273 - (35%) Gaps:90/273 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 PPHAQARVQPPARTKLTAQ-----QLGFQPEC------DILAREAISALQRAKTKDCREHIAQIA 110
            ||.|:..:...|...|.|:     :.|  |||      |....::.:|||..|           .
Mouse     3 PPAARLALLSAAALTLAARPAPGPRSG--PECFTANGADYRGTQSWTALQGGK-----------P 54

  Fly   111 CAIQAGRFYAPQLRSSCPAG-----------NHTANVS--------------------------- 137
            |......|..|......|.|           |...:||                           
Mouse    55 CLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGN 119

  Fly   138 LGCFKDEKDRRLLAGYYSSSKTSN--SPAKCVELCLQSGYPYAGVQYGRECFCGYDPPP-KASKL 199
            |||:||..:...|.|   :|||||  :...|:..|....:.:||::.|..||||.:|.. |..:.
Mouse   120 LGCYKDHGNPPPLTG---TSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKHGEA 181

  Fly   200 PDSSCNTKCLGNAKEICGGFYAMNIYETGI----AKFTAQLAATTPSEE------TKRV------ 248
            ..:.||:.|.|:..:.|||...:.:::|.:    ..::| :||...|.:      |.||      
Mouse   182 ASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSA-MAAVVYSPDFPDTYATGRVCYWTIR 245

  Fly   249 -----RIAFLLTL 256
                 ||.|..||
Mouse   246 VPGASRIHFNFTL 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
oxtNP_647705.1 WSC 138..218 CDD:280068 28/82 (34%)
Branch 250..503 CDD:280621 4/7 (57%)
Xylo_C 537..710 CDD:289306
Kremen1NP_115772.2 KR 31..114 CDD:238056 15/93 (16%)
WSC 119..200 CDD:280068 28/83 (34%)
CUB 214..320 CDD:238001 12/46 (26%)
Essential for apoptotic activity. /evidence=ECO:0000269|PubMed:26206087 414..473
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4157
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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