Protein Alignment oxt and XYLT1

DIOPT Version :10

• Sequence 1: NP_647705.1
• Gene: oxt / 38288
• FlyBaseID: FBgn0015360
• Length: 876
• Species: Drosophila melanogaster
• Sequence 2: NP_071449.1
• Gene: XYLT1 / 64131
• HGNCID: 15516
• Length: 959
• Species: Homo sapiens
• Alignment Length: 862
• Identity: 306/862 - (35%)
• Similarity: 433/862 - (50%)
• Gaps: 153/862 - (17%)

  Fly    36 DIVGGGSGSGFDAAEAPASPPPPHAQARVQPPARTKLTAQQLGFQPECDILAREAISALQRAKTK 100
            |.....|..|.|.:.      ||||:........||...     .|:|||..:||||||.|||:|
Human   221 DRAAANSSHGKDVSR------PPHARKTGGSSPETKYDQ-----PPKCDISGKEAISALSRAKSK 274

  Fly   101 DCREHIAQIACAIQAGRFYAPQLRSSCPAGNHTANVSLGCFKDEKDRRLLAGYYSSSKTSNSPAK 165
            .||:.|.:..|..:.|                                ||           .|.|
Human   275 HCRQEIGETYCRHKLG--------------------------------LL-----------MPEK 296

  Fly   166 CVELCLQSGYPYAGVQYGRECFCGYDPPPKASKLPDSSCNTKCLGNAKEICGGFYAMNIYETGIA 230
            ....|...|.....||:..:
Human   297 VTRFCPLEGKANKNVQWDED--------------------------------------------- 316

  Fly   231 KFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLE 295
              :.:.....|      |||||:|.::|||.||:.|:.||:|..:|.||||||:|.:||:|::|:
Human   317 --SVEYMPANP------VRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVDKRSNYLHRQVLQ 373

  Fly   296 LESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQ-SNWHWDFVINLSESDFPVKTLDKLVDF 359
            :..::.|:|:...|.:|||||||||:..||.|.|||: ::|.|||.||||.:|:|::|.|:||.|
Human   374 VSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAF 438

  Fly   360 LSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFV 424
            ||.....||:|.|||:..:||:|||||:.|:|||.||||:|||::|.||.|||||||..|:|.||
Human   439 LSRYRDMNFLKSHGRDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFV 503

  Fly   425 GYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNNLHVTNWKRKQGCKCQYK 489
            .|||.  ..|:|:..:.:.:.:|||||||||||||.|:.||.:.|||||.:|||.||.|||||||
Human   504 EYVTF--STDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGCKCQYK 566

  Fly   490 HVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWLYGPYTSEYANLHGY 554
            |:|||||||||||||:|:.|.|.|.:.: |||||||.|:||.::.||:.:|||.|.:....|..|
Human   567 HIVDWCGCSPNDFKPQDFHRFQQTARPT-FFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSY 630

  Fly   555 WQSLYHHEDVHGSGDDLARSIGDSVMRLSARQA------------KLYPLELIELTH-YLHRDQY 606
            |:::|...|...|..|:..::..|..||..|:|            :.||:......| |...|::
Human   631 WENVYDEPDGIHSLSDVTLTLYHSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRF 695

  Fly   607 KGFLVRYRARG-STGKPLHLETRVRPTQQGKLARNARFSKRLRNFEVSTDFDQKEQIARNFGKLL 670
            :|||:::.|.. :..|...|||.|.|.:..|:|.......||:..||.||:|.||::.||||.||
Human   696 QGFLIKHHATNLAVSKLETLETWVMPKKVFKIASPPSDFGRLQFSEVGTDWDAKERLFRNFGGLL 760

  Fly   671 GPQSDLLLSYTLQANADSGAASHSYNLTLLWIDPLGRLQDFNELHVEDSTSDVINHSKTLLKHPI 735
            ||..:       ...........:..:|::|:||:..:....::.:| ||:: ..|.|..|..|:
Human   761 GPMDE-------PVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIE-STAE-FTHYKPPLNLPL 816

  Fly   736 TPGIWTAKLIGRNSIYAQLKFLIAPLAYYKGYPLAKSSDAEALNAGLTVALPED--------FEM 792
            .||:||.|::......|:.|||:|||.:....|:......:..|..|..|..|.        ..:
Human   817 RPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLRNAYMEQSFQSLNPVLSL 881

  Fly   793 PVEWQQHLQTDDEQFTMREESLAKGKMLGQELHSWIDGLVGQFFQLRESCVVEADSEVSLPLCSD 857
            |:...|           .|::.......|..|..|:|.|||..:...:.|.....:...:..||.
Human   882 PINPAQ-----------VEQARRNAASTGTALEGWLDSLVGGMWTAMDICATGPTACPVMQTCSQ 935

  Fly   858 APWSSLAPDPKSDVDAL 874
            ..|||.:|||||::.|:
Human   936 TAWSSFSPDPKSELGAV 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:460348	8/79 (10%)
		Branch	250..504	CDD:452742	148/254 (58%)
		Xylo_C	537..709	CDD:463618	54/185 (29%)
XYLT1	NP_071449.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..259		12/48 (25%)
		Branch	328..581	CDD:452742	148/254 (58%)
		Xylo_C	613..792	CDD:463618	54/185 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	940..959		7/13 (54%)