DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oxt and GCNT4

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	NP_001353666.1	Gene:	GCNT4 / 51301	HGNCID:	17973	Length:	453	Species:	Homo sapiens

Alignment Length:	352	Identity:	90/352 - (25%)
Similarity:	152/352 - (43%)	Gaps:	54/352 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 NIYETGIAKFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQD 287
            :||:| :..:..:|.    |:|.|...||:.|.::..|: .|.||:.|:|...::|.||.|.:..
Human   111 DIYQT-LRGYAQKLV----SKEEKSFPIAYSLVVHKDAI-MVERLIHAIYNQHNIYCIHYDRKAP 169

  Fly   288 YLYRKLL-ELESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVK 351
            ..::..: .|...|.||.:|.|..:..:...|.|...|.|:.|||:|:..|.:||||...|||:|
Human   170 DTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLK 234

  Fly   352 TLDKLVDFLSANPGRNF---VKGHGRETQKFIQKQGLDKT---FVECDTHMWRIGDRKLPAGIQV 410
            :..:||..|....|.|.   ||....:.::|.....|.:.   :|:..... .|.....|..||:
Human   235 SNFELVSELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRT-NISKEAPPHNIQI 298

  Fly   411 DGGSDWVALSRPFVGYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLR---------NTKHCT 466
            ..||.:..||:.||.|:.    ::.::|......:.|..|.|.|:.|::|         .:....
Human   299 FVGSAYFVLSQAFVKYIF----NNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDV 359

  Fly   467 SYVDNNLHVTNWKRKQGC---KCQYKHVVDWC--GCSPNDFKPED--WPRLQATEQKSLFFARKF 524
            |.:.:...:..|...:|.   .|...|:...|  |.:...:..:|  |            ||.||
Human   360 SDLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHW------------FANKF 412

  Fly   525 ----EPVINQAVLLQLEE----WLYGP 543
                :|::.:.:..:|||    |:..|
Human   413 DSKVDPILIKCLAEKLEEQQRDWITLP 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068
		Branch	250..503	CDD:280621	71/273 (26%)
		Xylo_C	537..710	CDD:289306	4/11 (36%)
GCNT4	NP_001353666.1	Branch	133..402	CDD:332239	71/274 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156647
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840