DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oxt and Gcnt2

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	NP_001001511.1	Gene:	Gcnt2 / 306860	RGDID:	1303198	Length:	400	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	93/320 - (29%)
Similarity:	147/320 - (45%)	Gaps:	38/320 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 TTP-SEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLL-ELESKFP 301
            |:| |||.....:|:::.:. :......||.:|:|.|::||.:|||.:....:::.: .|.|.||
  Rat    83 TSPLSEEEADFPLAYVMVIY-KDFDTFERLFRAIYMPQNVYCVHVDSKAAETFKEAVRHLLSCFP 146

  Fly   302 NIRLARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVKTLDKLVDFLSANPGR 366
            |..||.:....::||.|.|...|.||.||:.|...|.:|||....|||:||..::|.:|....|:
  Rat   147 NAFLASRMERVVYGGFSRLQADLNCMRDLVASKVPWKYVINTCGQDFPLKTNKEIVQYLKGFKGK 211

  Fly   367 NFVKG-----HGRETQKFIQKQ--GLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFV 424
            |...|     |.....|::.|:  |.|..|:: :|:..:...   |..:.:..|:.:|||:|.||
  Rat   212 NLTPGVLPPEHVITRTKYVYKERKGRDGYFMQ-NTNTLKTPP---PHKLVIYFGTAYVALTRDFV 272

  Fly   425 GYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLR-----NTKHCTSYVDNNLHVTNWK--RKQ 482
            .::.    :|:....||:..:.|..|.|.|:.|:.|     ......|:. .||....||  ..|
  Rat   273 NFIL----NDKRAIDLLEWSKDTYSPDEHFWVTLNRIPGVPGAMPNASWT-GNLRAVKWKDMESQ 332

  Fly   483 GCKCQYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFE----PVINQAVLLQLEE 538
            ...|...:|.|.|.....|        ||........||.|||    |:..:.:.|:|.|
  Rat   333 NGACHGHYVHDICIYGNGD--------LQWLINSQSLFANKFEVNTYPLTVECLELRLRE 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068
		Branch	250..503	CDD:280621	77/267 (29%)
		Xylo_C	537..710	CDD:289306	1/2 (50%)
Gcnt2	NP_001001511.1	Branch	95..356	CDD:280621	79/278 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0799
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740