DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oxt and gly-16

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	NP_493135.2	Gene:	gly-16 / 173109	WormBaseID:	WBGene00001641	Length:	420	Species:	Caenorhabditis elegans

Alignment Length:	354	Identity:	77/354 - (21%)
Similarity:	126/354 - (35%)	Gaps:	84/354 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 SEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLL-ELESKFPNIRL 305
            |||..|..:::.| |..:.|.||..:|.::|.|::.|.|.|.|.....:..|| ||...|||:..
Worm    91 SEEEARFPLSYGL-LVYKELSQVLFMLSSIYQPQNEYCIAVGENSASTFLILLEELSDCFPNVHF 154

  Fly   306 ARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVKTLDKLVDFLSANPGRNFVK 370
             .||....||...::..:..|::.|.....:|.:...||..|.|:||..::|..|.:..|...|:
Worm   155 -MKRPPITWGSYEIINSVYDCLKFLSHLKSNWKYFQYLSGVDIPLKTNLEMVRILKSLNGTANVE 218

  Fly   371 GHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFVGYVTHPREDDE 435
            ....|.::.                   :|..:..:.:.:...|....:.|....|:.    ...
Worm   219 IKVYENRRL-------------------LGQNETESPLPLFKSSLSSLIPRKAANYLA----SSS 260

  Fly   436 LLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNNLHVTNWKRKQGCKCQYKHVVDWCGCSPN 500
            :.|.||:..|:|.:..|.|:.|:..|                           |.:.|    .|.
Worm   261 IPQQLLEFLRNTWVADEGFWGTLFGN---------------------------KGLFD----VPG 294

  Fly   501 DFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWLYGPYTSEYANLHGYW-QSLYHHEDV 564
            ....|:|          ::|.......:.:..    :.|.|      |.:.|..| :|..|:...
Worm   295 SLNFEEW----------IYFKENARANLTKPT----DGWFY------YISRHQIWFESGCHNHMK 339

  Fly   565 HGSGDDLARSIGDSVMRLSARQA---KLY 590
            .||   ....|||....|.|:..   |||
Worm   340 DGS---CVFGIGDVSNLLQAKALVAHKLY 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068
		Branch	250..503	CDD:280621	53/253 (21%)
		Xylo_C	537..710	CDD:289306	17/58 (29%)
gly-16	NP_493135.2	Branch	116..353	CDD:280621	63/314 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0799
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770