DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oxt and gly-18

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	NP_492014.4	Gene:	gly-18 / 172446	WormBaseID:	WBGene00001643	Length:	440	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	82/356 - (23%)
Similarity:	132/356 - (37%)	Gaps:	84/356 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 YAMNIYETGIAKFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDE 284
            |:.:..:|..:.|.......:|.||:..:....|:.   :.|.||..:|.::|.|::.|.|.|.|
Worm    91 YSTDRCQTLKSLFRFNKVPLSPEEESFPLSYGLLVY---KELSQVLFMLSSIYHPQNEYCIAVGE 152

  Fly   285 RQDYLYRKLL-ELESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDF 348
            ....:::.|| ||.:.|.||.. .||....||...::.....|:|.|......|.:...||..|.
Worm   153 NSAPIFQNLLKELSNCFSNIHF-MKRPPIDWGSHEIINSAYDCLEFLSHLKSDWRYFQYLSGVDI 216

  Fly   349 PVKTLDKLVDFLSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGG 413
            |:||..::|..|....|...|:....:.|:.   :|.::|              :.|..:.....
Worm   217 PLKTNLEMVQILKHLNGTANVEIKPYQYQRL---RGKNET--------------QSPLPLFKSSL 264

  Fly   414 SDWVALSRPFVGYVTHPRE------DDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNN 472
            |..:            |||      ...:.|.||:..|:|.:..|.|:.|:..| |:... :..:
Worm   265 SSLI------------PREAANHLSSSSIPQQLLEFLRNTGIADEGFWGTLFGN-KNLFD-IPGS 315

  Fly   473 LHVTNWKRKQGCKCQYKHVVDWCGCSPND------------FKPE---------------DWPRL 510
            |:...|       ..||:.|:.....|.|            .||.               |.|||
Worm   316 LNFKEW-------ISYKNNVETNLTYPTDGWRYYISRDQIWSKPNCHNYMKAGSCVFGIGDVPRL 373

  Fly   511 QATEQKSLF---FARKFEPVINQAVLLQLEE 538
              .:.|:|.   |..|.||   :|....|:|
Worm   374 --LKSKALVAHKFYLKSEP---EAYFCLLKE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068
		Branch	250..503	CDD:280621	61/271 (23%)
		Xylo_C	537..710	CDD:289306	1/2 (50%)
gly-18	NP_492014.4	Branch	136..373	CDD:280621	61/275 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0799
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770