DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oxt and Gcnt1

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	XP_006526742.1	Gene:	Gcnt1 / 14537	MGIID:	95676	Length:	432	Species:	Mus musculus

Alignment Length:	314	Identity:	80/314 - (25%)
Similarity:	143/314 - (45%)	Gaps:	41/314 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 IAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLE-LESKFPNIRLARKRFSTI 313
            ||:.:.::.: :..:.|||:|:|.|::.|.||||.:.:..:...:: :.|.|.|:.:|.:..|.:
Mouse   127 IAYSIVVHHK-IEMLDRLLRAIYMPQNFYCIHVDRKAEESFLAAVQGIASCFDNVFVASQLESVV 190

  Fly   314 WGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVKTLDKLVDFLSANPGRNFVKGHGRETQK 378
            :...|.:...|.||:||.:.|.:|.::|||...|||:||..::|..|..:.|.|     ..||:|
Mouse   191 YASWSRVKADLNCMKDLYRMNANWKYLINLCGMDFPIKTNLEIVRKLKCSTGEN-----NLETEK 250

  Fly   379 F--IQKQGLDKTFVECDTHMWRIGDRKLPAGIQVD--GGSDWVALSRPFVGYVTHPREDDELLQA 439
            .  .:::...|.:...|..:...|..|.|..::..  .||.:..::|.:||||.    ::|.:|.
Mouse   251 MPPNKEERWKKRYTVVDGKLTNTGIVKAPPPLKTPLFSGSAYFVVTREYVGYVL----ENENIQK 311

  Fly   440 LLKLFRHTLLPAESFFHTVLR----------NTKHCTSYVDNNLHVTNWKRKQG--------CKC 486
            |::..:.|..|.|..:.|:.|          :.|:..|.::.......|:..:|        ..|
Mouse   312 LMEWAQDTYSPDEFLWATIQRIPEVPGSFPSSNKYDLSDMNAIARFVKWQYFEGHVSNGAPYPPC 376

  Fly   487 QYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWL 540
            ...||...|.....|.   .|    ...|..| ||.||:..::...:..|:|.|
Mouse   377 SGVHVRSVCVFGAGDL---SW----MLRQHHL-FANKFDMDVDPFAIQCLDEHL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068
		Branch	250..503	CDD:280621	70/275 (25%)
		Xylo_C	537..710	CDD:289306	2/4 (50%)
Gcnt1	XP_006526742.1	Branch	127..395	CDD:396855	71/284 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847047
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0799
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740