DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oxt and xylt1

DIOPT Version :9

Sequence 1:	NP_647705.1	Gene:	oxt / 38288	FlyBaseID:	FBgn0015360	Length:	876	Species:	Drosophila melanogaster
Sequence 2:	NP_001120412.1	Gene:	xylt1 / 100145490	XenbaseID:	XB-GENE-949399	Length:	922	Species:	Xenopus tropicalis

Alignment Length:	818	Identity:	303/818 - (37%)
Similarity:	431/818 - (52%)	Gaps:	150/818 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PECDILAREAISALQRAKTKDCREHIAQIACAIQAGRFYAPQLRSSCPAGNHTANVSLGCFKDEK 145
            |:|:|..:||||||.|||:|.||:.||::.|..:.|:....::...||
Frog   218 PKCEITGKEAISALSRAKSKQCRQEIAEVYCQHKQGKLMPEKVTRLCP----------------- 265

  Fly   146 DRRLLAGYYSSSKTSNSPAKCVELCLQSGYPYAGVQYGRECFCGYDPPPKASKLPDSSCNTKCLG 210
                |.|     |:||:                 ||:                 .|.|..
Frog   266 ----LEG-----KSSNN-----------------VQW-----------------DDDSVE----- 282

  Fly   211 NAKEICGGFYAMNIYETGIAKFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPE 275
                          |.|                 ...|||||:|.::|||.||:.|:.||:|..:
Frog   283 --------------YPT-----------------VNPVRIAFVLVVHGRASRQLQRMFKAIYHKD 316

  Fly   276 HVYYIHVDERQDYLYRKLLELESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQ-SNWHWDF 339
            |.|:||.|:|..||:|::|:..|::||:|:...|.||||||||||:..||.|.|||: |:|.|||
Frog   317 HYYFIHCDKRSHYLHRQVLQFASQYPNVRVTSWRMSTIWGGASLLSTYLQSMRDLLEMSDWSWDF 381

  Fly   340 VINLSESDFPVKTLDKLVDFLSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKL 404
            .||||.:|:||:|.|:||.|||.....||:|.|||:..:||:|||||:.|:||||||||:||||:
Frog   382 FINLSAADYPVRTNDQLVAFLSRYRNMNFLKSHGRDNARFIRKQGLDRLFLECDTHMWRLGDRKI 446

  Fly   405 PAGIQVDGGSDWVALSRPFVGYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYV 469
            |.||.|||||||..|:|.||.|||.  .:|:|:..:.:.:.:|||||||||||||.|:.:|.:.|
Frog   447 PEGINVDGGSDWFLLNRKFVEYVTF--SNDDLVTKMKQFYSYTLLPAESFFHTVLENSPYCDTMV 509

  Fly   470 DNNLHVTNWKRKQGCKCQYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLL 534
            ||||.:|||.||.||||||||:|||||||||||||.|:.|.|.|.:.: |||||||.|:||.::.
Frog   510 DNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPSDFHRFQQTSRPT-FFARKFEAVVNQEIIG 573

  Fly   535 QLEEWLYGPYTSEYANLHGYWQSLYHHEDVHGSGDDLARSIGDSVMRLSARQA------------ 587
            ||:.:|||.|.|....|..||::||...|...|..|:..::..:...:..::|
Frog   574 QLDYYLYGNYPSGTPGLRSYWENLYDEPDGIHSISDVMLTMFHAFSHMGLKRAESSLHTDGENTC 638

  Fly   588 KLYPL-ELIELTHYLHRDQYKGFLVRYRARG-STGKPLHLETRVRPTQQGKLARNARFSKRLRNF 650
            :.||: ..:.:..|...|:::|||:::.|.. :..|...|||.|.|.:..|:|.......||:..
Frog   639 RYYPMGHPVSVHLYFLADRFQGFLIKHHATNLAVSKLETLETWVMPKKVFKIANPTSDFGRLQFS 703

  Fly   651 EVSTDFDQKEQIARNFGKLLGPQSDLLLSYTLQANADSGAASHSYNLTLLWIDPLGRLQDFNELH 715
            ||.|::|.||:|.||||.|:||..:.:.       ........:..:|::||||:..:....::.
Frog   704 EVGTEWDAKERIFRNFGGLMGPMDEPIA-------MQKWGKGPNITVTVVWIDPINVIAATYDIL 761

  Fly   716 VEDSTSDVINHSKTLLKHPITPGIWTAKLIGRNSIYAQLKFLIAPLAYYKGYP-----LAKSSDA 775
            :| ||:: ..|.|..|..|:.||:||.:::......|:.||||.||.:....|     |||....
Frog   762 IE-STAE-YTHYKPPLNLPLRPGVWTIRILHHWVPVAETKFLITPLTFSNRQPIKQEELAKFHGG 824

  Fly   776 EALNA-------GLTVALPEDFEMPVEWQQHLQTDDEQFTMREESLAKGKMLGQELHSWIDGLVG 833
            ...||       ||...|    .:||...|           .||:.....::|.:|.:.:|.|..
Frog   825 PPKNAYMEQSFQGLNPVL----NIPVNTAQ-----------VEEARKNAALVGAKLENLVDSLTS 874

  Fly   834 QFFQLRESCVVEADSEVSLPLCSDAPWSSLAPDPKSDV 871
            ..:...:.|.....|...:..|:...||||:|||||::
Frog   875 SMWSAVDICTTGPSSCPVMQSCAQTAWSSLSPDPKSEL 912

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxt	NP_647705.1	WSC	138..218	CDD:280068	9/79 (11%)
		Branch	250..503	CDD:280621	151/253 (60%)
		Xylo_C	537..710	CDD:289306	51/186 (27%)
xylt1	NP_001120412.1	Branch	291..543	CDD:280621	151/253 (60%)
xylt1	NP_001120412.1	Xylo_C	576..756	CDD:289306	51/186 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	339	1.000	Domainoid score	I1103
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32534
Inparanoid	1	1.050	545	1.000	Inparanoid score	I1133
OMA	1	1.010	-	-		QHG49999
OrthoDB	1	1.010	-	-		D258128at33208
OrthoFinder	1	1.000	-	-		FOG0003123
OrthoInspector	1	1.000	-	-		otm48881
Panther	1	1.100	-	-	O	PTHR46025
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2902
SonicParanoid	1	1.000	-	-		X616
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110