DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32301 and Gyc76C

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_001163473.1	Gene:	Gyc76C / 8674026	FlyBaseID:	FBgn0266136	Length:	1525	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	60/240 - (25%)
Similarity:	122/240 - (50%)	Gaps:	24/240 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 VYQNLVFQMAMKEEKALLDSIIPV--TLARSLQDAIASH----------IEEDPSNLMPFTKTRH 282
            |.:|.:.:|...:.|.::|.::.:  ..|.:|:|.:...          .|:....::|.:....
  Fly   816 VIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEK 880

  Fly   283 LFM----EP--HPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGD 341
            |.|    ||  :..|:|..:|:|.||.::.......:|..|::|:..||.........:::.:||
  Fly   881 LTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGD 945

  Fly   342 SYTCVTGIP-SYFPTHANACVNQALDMIEISRE--VSKRRNKKIDLRIGVHSGEILAGIIGLTKW 403
            :|..|:|:| .....||....:.||:::...::  ::.|.|:.:.||||:|:|.::||::|||..
  Fly   946 AYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMP 1010

  Fly   404 QFDIWSKDVDITNRLESSGLPGMVHISSR---TLGLLDNHYVYEE 445
            ::.::...|:..:|:||:|....:|||::   .|..|...|:.|:
  Fly  1011 RYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEK 1055

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	48/167 (29%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Gyc76C	NP_001163473.1	PBP1_Speract_GC_like	26..445	CDD:107365
		ANF_receptor	48..412	CDD:279440
		PK_GC-A_B	543..827	CDD:270944	3/10 (30%)
		HNOBA	<835..881	CDD:285003	5/45 (11%)
		CYCc	860..1052	CDD:214485	50/191 (26%)
		Guanylate_cyc	887..1074	CDD:278633	48/169 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453932
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830