DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32301 and Gucy2g

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_001074545.1	Gene:	Gucy2g / 73707	MGIID:	106025	Length:	1100	Species:	Mus musculus

Alignment Length:	263	Identity:	64/263 - (24%)
Similarity:	133/263 - (50%)	Gaps:	35/263 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 ALLDSIIP--VTLARSLQDAIASH----------IEEDPSNLMPFTKTRHLF----MEP-HPE-V 291
            ::|||::.  .|.|..|::.:...          :|:..|.::|......|.    :|| |.| |
Mouse   836 SILDSMMGKLETYANHLEEVVEERTRELVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESV 900

  Fly   292 SILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIP-SYFPT 355
            :|..:|:|.||.|.:......:|.:|::|:..||.....:...:::.:||:|...:|:| .....
Mouse   901 TIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHDVYKVETIGDAYMVASGLPIRNGAQ 965

  Fly   356 HANACVNQALDMIEISR--EVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRL 418
            ||:.....||.::.::.  ::.....:::.||||:|:|.::||::|:|..::.::...|::.:|:
Mouse   966 HADEIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRM 1030

  Fly   419 ESSGLPGMVHISSRTLGLL---DNHYVYEEGTDTAKLDPLLQRSNLSTYLIRSR------LPNFE 474
            |||.||..:|:|..|.|.|   ..:::.:.||.:.|     .:...:|:.::.:      ||.|.
Mouse  1031 ESSSLPLRIHVSQSTAGALLAAGGYHLQKRGTISVK-----GKGEQTTFWLKGKDGFPVPLPEFT 1090

  Fly   475 DTD 477
            :.:
Mouse  1091 EEE 1093

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	48/167 (29%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Gucy2g	NP_001074545.1	PBP1_GC_G-like	47..436	CDD:380595
		PK_GC	555..829	CDD:270894
		CYCc	865..1055	CDD:214485	51/189 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900