Protein Alignment CG32301 and ADCY10

DIOPT Version :9

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_060887.2
• Gene: ADCY10 / 55811
• HGNCID: 21285
• Length: 1610
• Species: Homo sapiens
• Alignment Length: 577
• Identity: 107/577 - (18%)
• Similarity: 194/577 - (33%)
• Gaps: 227/577 - (39%)

  Fly   215 QEYNMRS-----------GILSRYQ---VVYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIAS 265
            |:|.|.|           |.||..:   :|:.||:|:...|.|:          :..::|||. .
Human   266 QKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEE----------IGPAIQDAY-M 319

  Fly   266 HIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANH 330
            ||                       .|:|:.    |.|.            ::::|: ||
Human   320 HI-----------------------TSVLKI----FQGQ------------INKVFM-FD----- 339

  Fly   331 NRATRIKFLGDSYTCVTGIP-SYFP---THANACVNQALDMIEISREVSKRRNKKIDLRIGVHSG 391
                    .|.|:.||.|.| ...|   |||..|   |:|:.:...:|.|.:.    :.|||.||
Human   340 --------KGCSFLCVFGFPGEKVPDELTHALEC---AMDIFDFCSQVHKIQT----VSIGVASG 389

  Fly   392 EILAGIIGLT-KWQFDIWSKDVDITNRLESSGLPGMVHISSRTL-------------------GL 436
            .:..||:|.| :.::.:..:.|::..|: ....||:|...|.|.                   |:
Human   390 IVFCGIVGHTVRHEYTVIGQKVNLAARM-MMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGV 453

  Fly   437 LDNHYVYEEGTDTAKL--------------DPLLQRSNLSTYLIRSRLPNFEDTDDLEDDNFSLN 487
            .|:..:|:....|.|:              .|||.|:....|                   |...
Human   454 ADSGPLYQYWGRTEKVMFGMACLICNRKEDYPLLGRNKEINY-------------------FMYT 499

  Fly   488 DYRFSFSFSQD---YEDIQVKAQRDMILEVEHMPVNRVQTCKIRRPMHRIAKEDINEEYRFHLES 549
            ..:|..|.|..   ||.:....:..:::::|::...:         .|||....:| :..|| ::
Human   500 MKKFLISNSSQVLMYEGLPGYGKSQILMKIEYLAQGK---------NHRIIAISLN-KISFH-QT 553

  Fly   550 YYLFTTFRSWRMEWSFNKMRDLLMKYSLGMMVFAGATIIAMDLL---------VKSEAMDYTMLF 605
            :|....|.                           |.::.:|..         ::::.|  |:|.
Human   554 FYTIQMFM---------------------------ANVLGLDTCKHYKERQTNLRNKVM--TLLD 589

  Fly   606 SLFLLILLPLLLASYKKLWLRGRRLSPITQPTFFLSRWFIKASDLIEKSVFVRIPLAIMVLFLLY 670
            ..|..:                  |:.|....|.:||...:.|.|.::.   ::.:..|.:..|.
Human   590 EKFYCL------------------LNDIFHVQFPISREISRMSTLKKQK---QLEILFMKILKLI 633

  Fly   671 VMSSETVFSCDIARLELEIINSELHNLRPQMLCFMPWGVTYAVVIVLSLMLVIIGIP 727
            |.....:|..|    |.:.::|.......:::..:|      :.|::|| ...:.||
Human   634 VKEERIIFIID----EAQFVDSTSWRFMEKLIRTLP------IFIIMSL-CPFVNIP 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	39/179 (22%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
ADCY10	NP_060887.2	CHD	40..214	CDD:143636
		AcyC	<42..197	CDD:225025
		CHD	292..461	CDD:143636	51/240 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900