Protein Alignment CG32301 and NPR3

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_001191304.1
• Gene: NPR3 / 4883
• HGNCID: 7945
• Length: 541
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 66/318 - (20%)
• Similarity: 106/318 - (33%)
• Gaps: 98/318 - (30%)

  Fly   360 CVNQALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGL-TKWQFDIWS----------KDVD 413
            |.|:||  ..:...|:..|..|.||.:|.......|.:..| :.|...:.|          ||.:
Human   108 CGNRAL--FSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSE 170

  Fly   414 ITNRLESSGLPGMVHISSRTLGLLDNHY------VYEEGTDTAKLD-----------PLLQRSNL 461
            .::....:  |....:....|.|..:|:      ||.:.    ||:           .:.|...|
Human   171 YSHLTRVA--PAYAKMGEMMLALFRHHHWSRAALVYSDD----KLERNCYFTLEGVHEVFQEEGL 229

  Fly   462 STYLIRSRLPNFEDTDDLEDDNFSLNDYRFSFSFSQDYEDI--QVKA-QRDMILEVEHMPVNRVQ 523
            .|.:.     :|::|.||                  |.|||  .::| :|.:|:......:..:.
Human   230 HTSIY-----SFDETKDL------------------DLEDIVRNIQASERVVIMCASSDTIRSIM 271

  Fly   524 TCKIRRPMHRIAKEDINEEYR-FHLESYYLFTTFRSWRMEWSFNKMRDLLMK--YSLGMMVFAGA 585
            ....|..|       .:.:|. |::|   ||.:.......|......|...|  ||....|....
Human   272 LVAHRHGM-------TSGDYAFFNIE---LFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLR 326

  Fly   586 TI------IAMDLLVKSEA-------MDYTMLF--------SLFLLILLPLLLASYKK 622
            |:      .:|:  |||..       .||..:|        .|::|.|..:|.|.|.|
Human   327 TVKPEFEKFSME--VKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSK 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	22/101 (22%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	19/89 (21%)
		AcyC	681..1076	CDD:441717
		Nucleotidyl_cyc_III	841..1076	CDD:448371
NPR3	NP_001191304.1	PBP1_NPR_C	51..446	CDD:380609	66/318 (21%)
		TM_EphA1	476..507	CDD:214014