Protein Alignment CG32301 and NPR2

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_001365852.1
• Gene: NPR2 / 4882
• HGNCID: 7944
• Length: 1050
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 77/311 - (24%)
• Similarity: 136/311 - (43%)
• Gaps: 71/311 - (22%)

  Fly   159 VKNG-RAYFLGLAVSLFYFGYMALIDK-------ISTLDKVW-----ELTAYGAYLFFL------ 204
            |:|| |.||            ...||:       :..:::.|     |...:|....|:
Human   743 VRNGQRPYF------------RPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKE 795

  Fly   205 ---NMLCMFLSRFQEY--NMRSGILSRYQVVYQNLVFQMAMKEEK----ALLDSIIPVTLARSLQ 260
               ::|...|.|.::|  |:...:..|.|          |..|||    |||..|:|.::|..|:
Human   796 GGTSILDNLLLRMEQYANNLEKLVEERTQ----------AYLEEKRKAEALLYQILPHSVAEQLK 850

  Fly   261 DAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFD 325
                              :...:..|....|:|..:|:|.||.|:.......:|.:|::|:..||
Human   851 ------------------RGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFD 897

  Fly   326 LAANHNRATRIKFLGDSYTCVTGIPS-YFPTHANACVNQALDMIEI--SREVSKRRNKKIDLRIG 387
            ...::....:::.:||:|..|:|:|. ....||......||.:::.  |..:..|.:.::.||||
Human   898 AIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIG 962

  Fly   388 VHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLD 438
            ||:|.:.||::||...::.::...|:..:|:||:|....:|:||.|...||
Human   963 VHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALD 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	77/311 (25%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	47/159 (30%)
		AcyC	681..1076	CDD:441717
		Nucleotidyl_cyc_III	841..1076	CDD:448371
NPR2	NP_001365852.1	PBP1_NPR_B	26..421	CDD:380607
		PK_GC-A_B	521..795	CDD:270944	12/63 (19%)
		HNOBA	<801..849	CDD:462234	17/57 (30%)
		CYCc	828..1012	CDD:214485	55/201 (27%)