Protein Alignment CG32301 and Ac3

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: XP_061511365.1
• Gene: Ac3 / 4578014
• VectorBaseID: AGAMI1_012876
• Length: 1207
• Species: Anopheles gambiae
• Alignment Length: 1121
• Identity: 306/1121 - (27%)
• Similarity: 491/1121 - (43%)
• Gaps: 235/1121 - (20%)

  Fly    43 CHLVSVALVTQLIIVIEILMLIHVILLFSVVKNIDFLTVLPYFAVMLLTPSILMPSREPNVEQYE 107
            |:|::..|.....|.:.....:..|::.||     |||:....|::|         |.....::.
Mosquito    44 CYLIASILFDVWAIAVPQGQSVESIVVTSV-----FLTINIVLAIVL---------RFCGRGRFR 94

  Fly   108 SIAILVSCLMALLLTAMDLILPICYFRPFSLVP--SYDHVVIV--LIYLMFPIAFVKNGRAYFLG 168
            .:...::..:|.||....|.|.:  |...|:.|  |....|::  |:|:..|:.....|  ..||
Mosquito    95 GVIWEIAPHLAWLLAIKQLFLQL--FLKGSVTPRDSLGWAVLLNFLVYVTLPVLLKYTG--ILLG 155

  Fly   169 LAVSLFYFGYMALIDKISTLDKVWELTAYGAYLF----FLNMLCMFLSRFQEYNMRSGILSRYQV 229
            |.....|..  |:|......:..||.......|.    .:.:||.||:   |...|...|...|.
Mosquito   156 LGSFATYVN--AIIGLAKKENYFWEQQVANILLLIAATLIGLLCYFLA---EAKQRRAFLEAKQG 215

  Fly   230 VYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSIL 294
            :...::.:....|::.||.|::|..:|..::..:.|      :|...|.|   ::|..|..||||
Mosquito   216 LEVKMLIEEQSAEQERLLLSVLPEHVAVKMRQDLGS------TNSEQFKK---IYMSRHENVSIL 271

  Fly   295 EADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPTHANA 359
            .||:|.||.:::|....|||.||:|||..||..|...:..|||.|||.|.|::|.|...|.||..
Mosquito   272 YADIVGFTAISSTYSAQDLVKILNELFARFDRLAEKYQQLRIKILGDCYYCISGAPVERPDHAVL 336

  Fly   360 CVNQALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLP 424
            ||:..|.|::..:.|.::.|..:|:|:|:|:|.:||||:|..:||||::||||::.|::||||..
Mosquito   337 CVHMGLSMVKAIKYVQQKTNSPVDMRVGIHTGAVLAGILGQRQWQFDVYSKDVELANKMESSGKA 401

  Fly   425 GMVHISSRTLGLLDNHYVYEEGTDTAKLDPLLQRSNLSTYLIRSRLPNF---------------- 473
            |.||:|.:|||.|:..:..|.... .|.:..|:.:.|.||.|...|..|
Mosquito   402 GRVHLSEKTLGFLNGEFEVEPAFG-EKREEALRIAGLKTYFITKVLKPFCPSEHKNGSADPKDVV 465

  Fly   474 -----------EDTDD------------------------LEDDNFSLNDYRFSFSFSQDYEDIQ 503
                       ||.||                        ||||             :|..||.:
Mosquito   466 IEPDGPSEILREDDDDTKPANGANAGDEPSTPGTDDKTDPLEDD-------------TQASEDYK 517

  Fly   504 VKAQRDMILEVEHMPVNRVQTCKIRRPMHRIAKEDINEEYRFHLESYYLFTTFRSWRMEWSFNKM 568
            ::.:::::....|..:::..|                           :|.||.....|.::|:.
Mosquito   518 MRLRKELVSRDGHSEISKDTT---------------------------IFLTFNDKTHETAYNEY 555

  Fly   569 RDLLMKYSLGMMVFAGATIIAMDLLVKSEAMDYTMLF----SLFLLILLPLLLASYKKLWLRGRR 629
            |:   .:|        |..:...|||:..|:.|.:|.    ::...|::|.|:..:..::
Mosquito   556 RE---PHS--------AVPLLAALLVQFVAILYALLVLPRTAVHFEIVIPPLVIIFVMVF----- 604

  Fly   630 LSPITQPTFFLSRWFIKASDLIEKSVFVRIPLAIMVLFLLYVMS-SETVFSCDIARLELEIINSE 693
            :|.....|..|..:....|.....|..:|...||:::.||.|.: |:.:.:.....|.|.|.|..
Mosquito   605 ISVAESLTGILPAFITLNSKRYNDSTSLRKSTAIIIVLLLGVSNVSDMLAASHRTPLSLNITNVS 669

  Fly   694 LHN--LRPQMLCFMP-WGVTYAVVIVLSLMLVIIGIPLIIKLGVGLAILGSHVIT-VHAYYGFAF 754
            ..:  :.|..:|..| :...|.|       |::|...:|.:|.....||...:|| :|.|.....
Mosquito   670 FASTEMEPASVCLFPSYFSNYTV-------LILIATSIITQLSHLSKILLMIIITAIHCYVNIFH 727

  Fly   755 --ERSQTTNIGVTSSLAHSWYMVAFFIVVVVREGYL-NYILKASYFMSM----CFEKKHELTKVK 812
              |..:..:.|:.:.....:.:.|..:.|.:...:| .:|.|....:.|    ..::|.:.:.::
Mosquito   728 LDEAFRNEDFGIMNVFPLRYTLSALLVAVTIALSFLARHIDKVDRVIFMWKTEVIDQKEKASDMR 792

  Fly   813 TRTIKIIMANILPTHVAEVFK-VRRRS-DQLYYENFSQVAVMFATIENYE-------ADKSG--- 865
            .|. :.::.|:||.||||.|. .|:|| |.||.:::::|.|:||::.|:.       .:..|
Mosquito   793 RRN-EALVYNVLPMHVAEHFMGNRKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEETVNNQGLEC 856

  Fly   866 LRALHEMICYFDELLVNYQSWYKIEKIKVMGWTYLAACGLHVDHYTDFSVSVPISTNRESDKLQK 930
            ||.|:|:|..||.|| ....:..|.|||.:|.||:||.||:           |....:..|.:
Mosquito   857 LRFLNEVISDFDALL-ELPQFQDIIKIKTIGSTYMAASGLN-----------PSRIVKPDDPV-- 907

  Fly   931 SGSVRFAPMDGDEIMIKDLHPTQATTNEDDNTILVMTEFALNLLRILRDIRSKGI--FFEKDSKL 993
              |||:|            |            :.::.||||.|.:.|:.|..:..  |.
Mosquito   908 --SVRWA------------H------------LALLVEFALELKKALQGINEQSFNHFV------ 940

  Fly   994 TGSLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANVLRDFNIRCT 1058
               ||:|:.|||:.|||:|..||||||||:|||:||||.|||....|.|||.|..:|:.|.....
Mosquito   941 ---LKMGVNHGPITAGVIGARKPHYDIWGNTVNVASRMESTGKAGAIQVTEETCQILQTFGYTFE 1002

  Fly  1059 YRGMTFVKGVGQVPTY 1074
            .||:..|||.||:.||
Mosquito  1003 QRGLVAVKGKGQLMTY 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	124/401 (31%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	73/155 (47%)
		AcyC	681..1076	CDD:441717	128/419 (31%)
		Nucleotidyl_cyc_III	841..1076	CDD:448371	87/246 (35%)
Ac3	XP_061511365.1	None