Protein Alignment CG32301 and CG43373

DIOPT Version :9

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Alignment Length: 1112
• Identity: 294/1112 - (26%)
• Similarity: 488/1112 - (43%)
• Gaps: 233/1112 - (20%)

  Fly    53 QLIIVIEILMLIHVILLFSVVKNIDFLTVLPYFAVMLLTPSILMPSREPNVEQYESIAILVSCLM 117
            |||.:| ::.:...:|:|.:|..|..: |..:...:|..|::           .|...:|||.::
  Fly   511 QLIPLI-LMQVDESVLVFLIVMLICGI-VYAFLLCILSKPAM-----------NEIFLVLVSYVI 562

  Fly   118 ALLLTAMDLILPICYFRPFSLVPSYDH----VVIVLIYLMFPIAFVKNGRAYFLGLAVSLFYFGY 178
            .....|:::.:      .:::.||...    ..|||||:.:.:..::...|...|:.:|:.:. |
  Fly   563 LGTFLAIEVAV------SYAMQPSKSFNGSACCIVLIYMTYTMLPLRLREALIGGILLSVVHL-Y 620

  Fly   179 MALIDKISTL-DKV-----W-ELTAYGAYLFFLNMLCMFLSRFQEYNMRSGILSRYQVVYQNLVF 236
            ..|  :::.: |:.     | ||......|...|:..::....:|...|...:...|.:...|..
  Fly   621 TCL--RLNAMQDEAVEMIHWEELLCTLVALLLANLTGVYTHWPKEKAQRKAFIETRQCIEARLRT 683

  Fly   237 QMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDF 301
            |...::::.||.|::|..:|..::|.||....:        |:...::::.|..||||.||:..|
  Fly   684 QRENQQQERLLLSVLPRHVAMEMKDDIAGQPRD--------TQFHKIYIQRHENVSILFADICGF 740

  Fly   302 TGLTTTMEVSDLVAILHELFVSFD-LAANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVNQAL 365
            |.|:......:||.:|:|||..|| |||.|: ..|||.|||.|.||:|:|...|.||:..|...|
  Fly   741 TSLSDQCTAEELVRLLNELFARFDRLAAEHH-CLRIKLLGDCYYCVSGLPEPRPDHAHCAVEMGL 804

  Fly   366 DMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHIS 430
            |||:....|.:.....:::|:|:|:|.:..|::||.|||||:||.||.:.|.:||.|:||.|||:
  Fly   805 DMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHMESGGIPGRVHIT 869

  Fly   431 SRTLGLLDNHYVYEEGTDTAKLDPLLQRSNLSTYLI------------RSRLP---NF------- 473
            ..||..||..|..|.|....: :..|:...:.||||            |:||.   |.
  Fly   870 KETLKCLDGDYEVEVGKGNER-NSYLKDHQIETYLIVPGDIYRPHKKSRNRLQVNGNISKELRMM 933

  Fly   474 -EDTDDLEDDNFSLNDYRFSFSFSQDYEDIQVKAQRDMILEV-EHMPVNRVQTCKIRRPMHRIAK 536
             ..|.......|...|   |...::|.||           || |::             |..|..
  Fly   934 GHGTAQKHTSKFGFGD---SSESAKDPED-----------EVNEYL-------------MRAIDA 971

  Fly   537 EDINEEYRFHLESYYLFTTFRSWRMEWSFNKMRDLLMKYSLGMMVFAGATIIAMDLLVKSEAMDY 601
            ..|:.....|.:|..|.........:::....|.|.:.:...::|..|.:|  |.|:|...:: .
  Fly   972 RSIDHLRAEHCQSLLLCFKDNVLERKYASEPDRMLCVYFYCSLLVLLGTSI--MRLVVFQSSL-L 1033

  Fly   602 TMLFSLFLLILLPLLL-------------ASYKKLWLR---GRRLSPITQPTFFLSRWFIKASDL 650
            |:..|...|:||..|:             :..|:..||   .||:|
  Fly  1034 TLALSTGALLLLGFLVFLVACHKINFQLPSDIKRFSLRIHSNRRIS------------------- 1079

  Fly   651 IEKSVFVRIPLAIMVLFLLYVMSSETVFSCDI---ARLELEI----------INSELHNL-RPQM 701
               .:|....:|::||..|..|..|:....::   .|..|::          :|:::::. .|..
  Fly  1080 ---QLFAFASVALIVLTTLLAMFQESGRQMELLQRRRFWLDVNGSISLNDTELNTKMYDAEEPDC 1141

  Fly   702 LCFMPWGVTYAVVIVLSLM--LVIIGIPLIIKLGVGLAILGSHVITVHAYYGFAFERSQ--TTNI 762
            ..::.:. |:.::.:||:|  .....:.:::||.:.|...||::......|..:.|.||  ....
  Fly  1142 DFYLAYN-TFLLLTLLSMMSCATYQVLRILLKLLLLLLASGSYMACSSNLYSRSREMSQELANEE 1205

  Fly   763 GVTSSLAHSWYMVAFFIVVVVREGYLNYILKASYFMSMCF-----EKKHELTKVKTRTIKIIMAN 822
            .:...:..|.::.||.:.::    :.::..:|:|.:...:     |:|.::..::....| ::.|
  Fly  1206 ALLRYIIDSIFLFAFMLALI----FHSHQTEATYRLDFIWKLQATEEKEDMEHLQAYNRK-LLEN 1265

  Fly   823 ILPTHVAEVFKVRRRS-DQLYYENFSQVAVMFATIENY-------EADKSG---LRALHEMICYF 876
            |||.||||.|..|.:. |.||:|....|.::||:|.|:       |.:..|   ||.|:|:|..|
  Fly  1266 ILPVHVAEHFLSREKHLDDLYHEQCDSVCILFASIPNFSEFYVELEGNNEGVECLRLLNEIIADF 1330

  Fly   877 DELLVNYQSWYKIEKIKVMGWTYLAACGLHVDHYTDFSVSVPISTNRESDKLQKSGSVRFAPMDG 941
            |||| :.:.:..|||||..|.||:||.||               |....|::..|
  Fly  1331 DELL-SEERFRCIEKIKSTGATYMAASGL---------------TANTCDRVNFS---------- 1369

  Fly   942 DEIMIKDLHPTQATTNEDDNTILVMTEFALNLLRILRDIRSKGIFFEKDSKLTGSLKIGIAHGPV 1006
                    |.|            .|.::||.|...:.::       ...|.....::|||..|||
  Fly  1370 --------HVT------------AMADYALQLFDKIEEV-------NMHSFNNFRMRIGINIGPV 1407

  Fly  1007 MAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANVL--RDFNIRCTYRGMTFVKGVG 1069
            :|||:|..||.|||||:.||:||||.|||:.|.|.||:....:|  |.|.:.|  ||...|||.|
  Fly  1408 VAGVIGACKPQYDIWGNAVNVASRMDSTGLVDHIQVTQEMQQILEGRGFELTC--RGSVDVKGKG 1470

  Fly  1070 QVPTYLV 1076
            .:.||.:
  Fly  1471 SMITYFL 1477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	70/156 (45%)
		CYCc	812..1051	CDD:214485	85/251 (34%)
		Nucleotidyl_cyc_III	841..1076	CDD:299850	84/246 (34%)
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	44/225 (20%)
		CYCc	686..881	CDD:214485	80/203 (39%)
		Guanylate_cyc	722..895	CDD:278633	74/174 (43%)
		DUF1053	<949..1005	CDD:283888	14/82 (17%)
		CYCc	1259..1455	CDD:214485	85/249 (34%)
		Guanylate_cyc	1285..1479	CDD:278633	84/248 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453905
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D57794at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940