Protein Alignment CG32301 and Ac3

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Alignment Length: 1130
• Identity: 307/1130 - (27%)
• Similarity: 500/1130 - (44%)
• Gaps: 240/1130 - (21%)

  Fly    43 CHLVSVALVTQLIIV-----IEILMLIHVILLFSVVKNIDFLTVLPYFAVMLLTPSILMPSREPN 102
            |.|::...:|.|:.:     ...|...|.|||..|.:.:..|::| :|.|.:    ||.||..|
  Fly   101 CMLLAYLALTALLHIGRRSDKPALRRFHQILLIIVPRALWLLSIL-HFTVYV----ILQPSFSP- 159

  Fly   103 VEQYESIAILVSCLMALLLTAMDLILPICYFRPFSLVPSYDHVVIVLIYLMFPIAFVKNGRAYFL 167
             ......|||::.|:                        |..:.:.||:|...|..:    .||:
  Fly   160 -RDLLGWAILLNFLV------------------------YVTLPLQLIFLGLSIGCI----TYFI 195

  Fly   168 GLAVSLFYFGYMALIDKISTLDKVWELTAYGAYLFFLNMLCMFLSRFQEYNMRSGILSRYQVVYQ 232
            .|::.:.|..:.:|:......:.|...||     ..:.:|..|:.   |...:...|...:.:..
  Fly   196 CLSLPVGYSHWDSLLSNQLAANAVLIATA-----ALIGLLYYFMG---EAKQKRAFLEAKKSLEV 252

  Fly   233 NLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEAD 297
            .:|.:....|::.||.|::|..:|..:::.:.|...|      .|.|   ::|..|..||||.||
  Fly   253 KMVIEEQSAEQERLLLSVLPKHVAIKMREDLGSSSSE------AFKK---IYMSRHENVSILYAD 308

  Fly   298 MVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVN 362
            :|.||.:::|....|||.:|:|||..||..|...:..|||.|||.|.|::|.|...|.||..||:
  Fly   309 IVGFTAISSTYSAQDLVKMLNELFARFDRLAEKYQQLRIKILGDCYYCISGAPDERPDHAVLCVH 373

  Fly   363 QALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMV 427
            ..|.|::..:.|.::.|..:|:|:|:|:|.:||||:|..:||||::||||::.|::||||..|.|
  Fly   374 MGLSMVKAIKYVQQKANSPVDMRVGIHTGAVLAGILGQRQWQFDVYSKDVELANKMESSGKAGRV 438

  Fly   428 HISSRTLGLLDNHYVYEEGTDTAKLDPLLQRSNLSTYLIRSRL---------------------- 470
            |||.:||..|:..:..|.... .|.:.||:.:.|.||.|...:
  Fly   439 HISDKTLAFLNGEFEVEAAFG-EKREELLRIAGLKTYFITKVVKAFASPCAKKINETQAEIAHPN 502

  Fly   471 PNFEDTD---DLEDDNFSLNDYRF--SFSFSQDYE-DIQVKAQRDMILEVEHMPVNRVQTCKIRR 529
            ||...||   |.:|::.:|:|...  ..|.|..:: .|.|.|..:..:::|:.. .|::...:.|
  Fly   503 PNGSTTDIVSDEDDNDATLDDEELLAQNSVSNGHQIGIAVTADEEEQVKLENFK-QRLKDELVTR 566

  Fly   530 PMHRIAKEDINEEYRFHLESYYLFTTFRSWRMEWSFNKMRDLLMKYSLGMMVFAGATIIAMDLLV 594
            ..|....:|.|           :|..|::.::|..:...|:   .|| .:.:.|...:..:|:|.
  Fly   567 DGHENLTKDTN-----------IFLRFKNPQLEQLYAVYRE---PYS-SLPLLAALLVQCIDVLY 616

  Fly   595 KSEAMDYTMLFSLFLLILLPLLLASYKKLWLRGRRLSPITQ-------PTF--FLSRWFIKASDL 650
            ....:..:.|.  |:.|..||:               ||..       .:|  .|.::|:..|..
  Fly   617 SYLVLPRSTLH--FINIAAPLV---------------PIAMLVVISLAESFSGMLPKFFVDVSKR 664

  Fly   651 IEKSVFVR------IPLAI-------MVLFLLYVMS----SETVFSCDIARLELEI-------IN 691
            .....|||      |.|.|       |..|:.:|.:    ||:.|:. .|.||.:|       :.
  Fly   665 FNDITFVRELAAIIIALTIGFSNVIDMFFFVTFVRTEHIVSESEFNV-TASLESDINLVVEGMVT 728

  Fly   692 SELHNLRP-----QMLCFMPW-GVTYAVVIVLSLMLVIIGIPLIIKL-GVGLAILGSHVITVHAY 749
            :|  :|.|     ||...:|. .|.|...:....:|::|.|.:|.:| .:...:|...:..:|.|
  Fly   729 AE--HLLPASFVEQMRDAVPTERVLYPSYLSNFGVLILIAIAVIAQLTHLTKILLLLSIAALHCY 791

  Fly   750 YG-------FAFERSQTTNIGVTSSLAHSWYMVAFFIVVVVREGYLNY----ILKASYFMSMCFE 803
            :.       :|.|........:::..|.|..::...:.:.....::::    |.|   :.:...|
  Fly   792 FNIFIMQDLYALEDDFEHQPIISTRYAASGLLLVAALALSTLARHMDHEDRVIFK---WKTEVAE 853

  Fly   804 KKHELTKVKTRTIKIIMANILPTHVAEVF--KVRRRSDQLYYENFSQVAVMFATIENYE------ 860
            :|.....::.|. :.::.|:||.||||.|  ..:|..|.||.:::::|.|:||::.|:.
  Fly   854 QKETANDMRQRN-EALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEE 917

  Fly   861 -ADKSG---LRALHEMICYFDELLVNYQSWYKIEKIKVMGWTYLAACGLHVDHYTDFSVSVPIST 921
             .:..|   ||.|:|:|..||.|| ....:..|.|||.:|.||:||.|::|..
  Fly   918 TVNNQGLECLRFLNEVISDFDALL-ELPQFQDIIKIKTIGSTYMAASGINVQR------------ 969

  Fly   922 NRESDKLQKSGSVRFAPMDGDEIMIKDLHPTQATTNEDDNTILVMTEFALNLLRILRDIRSKGI- 985
                       :||                ..|...|..:.:.::.||||.|...|:.|..:..
  Fly   970 -----------TVR----------------NDAPITERWSHLAILVEFALELKHALQSINEQSFN 1007

  Fly   986 -FFEKDSKLTGSLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANV 1049
             |.         ||:||.|||:.|||:|..||||||||:|||:||||.|||....|.|||.|.|:
  Fly  1008 HFV---------LKMGINHGPITAGVIGARKPHYDIWGNTVNVASRMESTGKAGAIQVTEETCNI 1063

  Fly  1050 LRDFNIRCTYRGMTFVKGVGQVPTY 1074
            ||.|......||:..|||.||:.|:
  Fly  1064 LRLFGYTFLQRGLVAVKGKGQLMTF 1088

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	121/398 (30%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	72/155 (46%)
		AcyC	681..1076	CDD:441717	125/433 (29%)
		Nucleotidyl_cyc_III	841..1076	CDD:448371	86/246 (35%)
Ac3	NP_610116.2	AcyC	122..455	CDD:441717	119/384 (31%)
		Guanylate_cyc	294..476	CDD:425528	79/182 (43%)
		Guanylate_cyc	892..1092	CDD:425528	86/246 (35%)