Protein Alignment CG32301 and Ac13E

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Alignment Length: 1568
• Identity: 298/1568 - (19%)
• Similarity: 484/1568 - (30%)
• Gaps: 689/1568 - (43%)

  Fly   106 YESIAILVSCLMALLLTAMDLILPICYFRPFSLVPSYDHV--VIVLIYLMFPIAFVKNGRAYFLG 168
            |.....:.|.:.||||....|.......|.||.:..:...  :::|||...|:..       :||
  Fly   149 YREHRTVTSAVTALLLCGASLAFLTYTGRAFSPLGHFAICLEIVLLIYTALPMPL-------WLG 206

  Fly   169 LAVSLFYFGYMALIDKI------------------------------STLDKVWELTAY-GAYLF 202
            .:.::.|.....::..:                              |....:..:.|: ..:|.
  Fly   207 ASTAISYSIAFEMVSHMVIGCSAIHGGPMHGGGGAAGGSGMEANGDPSNRILILRIMAHLSVHLV 271

  Fly   203 FLNMLCMFLSRFQEYNMRSGILSRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHI 267
            .:::|.|.|.|.:...|:.|         |||:.:..::.||.|.:.:|...:...:.|.:.:
  Fly   272 GVHVLIMNLVRMRGTFMKVG---------QNLLVRRQLEMEKQLKEKMIHSVMPPKVADMLLN-- 325

  Fly   268 EEDPSNL----MP----------FTKTRHLF----MEPHPEVSILEADMVDFTGLTTTMEVSDLV 314
            |..||.|    :|          ....:.||    |.....||||.||:|.||.:::|.....||
  Fly   326 EGGPSGLDAGGLPPESHYMRPRASNDVKSLFRPFHMHSMENVSILFADIVGFTRMSSTKTAEQLV 390

  Fly   315 AILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVNQALDMIEISREVSKRRN 379
            .||::||..||...:.:...:|..|||.|.||:|.|.....||..||...|.||:..|....:|:
  Fly   391 EILNDLFERFDDLCSLSGCEKISTLGDCYYCVSGCPEPRADHAICCVEMGLGMIDAMRCFDAQRH 455

  Fly   380 KKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNHYVYE 444
            :.:.:|:|||:|.:|.||:|..:.:||:||.||.:.|::||||.|..||||..|...|.:.|..|
  Fly   456 EGVKMRVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMESSGKPEQVHISQETSSFLGDAYYLE 520

  Fly   445 EG------------------TDTAKLDP-------------------LLQRSNLSTYLIRSRLPN 472
            ||                  |.|..|.|                   .|.:|..:...::..:|.
  Fly   521 EGEEVFGHRTYFVVGRRRDFTRTNSLSPSMPANATGSSLLLPGAHGASLSQSATNVSAVQPNVPP 585

  Fly   473 FEDTDDLEDD--------------NFSLNDYRFSFSFSQDYED-------------IQVKAQRDM 510
            ......|...              :.|:...:.|.|..:|.|.             |.|:.:..:
  Fly   586 ASPVGQLSSSLNPSPVLSMRPRLTSLSMKMRKKSQSRDRDVERGIIHPAAAGIPPVIVVRERPKI 650

  Fly   511 ILEVEHMPVN----------------------------RVQTCKIRRPMHRI------------- 534
            |:..:.:|.:                            :::..||.|.:.|.
  Fly   651 IITTKSLPGSLDSDEQPPVSPPLLPPANPPAAETRSKIKLKVWKIPRFLKRFEDLTNRSSCGGSS 715

  Fly   535 ---------------AKEDINEEYRFHLESYYLFTTFRSWRMEWSFNKMRD----------LLMK 574
                           .||::::..:.:.|....|..          |:|::          :|::
  Fly   716 SAGHLDKEREREREKEKEELHQHNQLNPEETLAFMD----------NQMQNGNGCGYQQLPVLVE 770

  Fly   575 YSLGMMVF------------AGATIIAMDLLVKSEA--------------------MDYTMLFSL 607
            .:......            |.:|.:|..:|...||                    :|.....|.
  Fly   771 SNHRTQTLDIPAARPVLHHAATSTALASSVLRSPEAGVSGGGGCCSPGQYSMYDDIIDVRSYISQ 835

  Fly   608 FLLILLPL-LLASYKK-----------------LWLRGR-------------------------- 628
            ....:.|. ...||:.                 :...||
  Fly   836 SRSDISPFGRSGSYRSQCGRQSTGGVNGAGPAGVGAEGRAGTSQTAPPVEQSPLPRPRASTLATG 900

  Fly   629 ----------------------------------------------------------RLSPITQ 635
                                                                      |.|.|.|
  Fly   901 RPTPNSLEPGPSSTSPCCLPAPGNSVGGGGIFPPTHSRQSSICPSATSRKDSGIKSNSRRSSIQQ 965

  Fly   636 PTFFLSRWFI------------------------------------------------------- 645
            ..:.|::..|
  Fly   966 QIYALNQTAISQHRVSGYFTSSTSSISNLGEVQGLGLPLAVQPPPPLLMPACSSQMADPLAACLQ 1030

  Fly   646 ---KASDL---------------------------------IEK--------------------- 653
               |.|||                                 :|:
  Fly  1031 QLRKQSDLQLIRCVRDNARSQRSYLVKPPLRKFSLYFKSRQLERDFRSKAHRFGAENETEGPPTL 1095

  Fly   654 ---------SVFVRIPLAIMVLFLLYVMSSETV----------FSC------------------- 680
                     .:||.|.:.:.:...|::|:..||          |||
  Fly  1096 ATPRYNTYIDIFVGIAVYLCISVSLFLMTQNTVSPSFRLWVTLFSCFTGIQVFALFLFTRQMCRR 1160

  Fly   681 ------------------DIARLE------------------LEIINSELHNLRPQMLCFMPWGV 709
                              |:.|.|                  .|.|:|           :.||.:
  Fly  1161 QSGSNVSNRFRSKSTTSEDLERDERGAAPGGRPHFESCADRIFEAISS-----------WYPWHI 1214

  Fly   710 TYAVVIVLSLMLVIIGIPLIIKLGVGLAILGSHVITVHAYYGFA-------FERSQTTNIGVTSS 767
            ..||::.:.::|:|... |::.|        ..:.....:|||.       |......|..|.:.
  Fly  1215 CLAVLMAMPVLLIIANF-LLLDL--------EQLEAFEYHYGFLIFVCIVHFCNFTQLNCWVRNV 1270

  Fly   768 LAHSWYMVAF-FIVVVVR---------------------------------EGYLN--YILKASY 796
            ||   ::.|. ||.:.|.                                 |.||:  .||...:
  Fly  1271 LA---FLAALCFIGIAVSQLMVYSHNRSDQQQDQEASNFIQEIKWFQDYHVEIYLDLLLILVLVW 1332

  Fly   797 FMSMCFEKKHELT----------KVKTRTIK----IIMANILPTHVAEVFKVRRRSDQLYYENFS 847
            |::..||..:.||          ||:.:.:|    :::.||:|.||||..|    :...|.||..
  Fly  1333 FLNREFEIGYRLTFYGNAVANQDKVRVQNMKNQADMLLHNIIPKHVAEHLK----NTAKYSENHH 1393

  Fly   848 QVAVMFATI--------ENYEADKSGLRALHEMICYFDELLVNYQSWYKIEKIKVMGWTYLAACG 904
            .:|::||:|        |:|...|..||.|:|:|..||||| :...:..:||||.:|.|::||.|
  Fly  1394 NIAIIFASIVNFNEMYDESYLGGKEFLRVLNELIGDFDELL-SRPEFRAVEKIKTIGSTFMAASG 1457

  Fly   905 LHVDHYTDFSVSVPISTNRESDKLQKSGSVRFAPMDGDEIMIKDLHPTQATTNEDDNTILVMTEF 969
            |...|                                           :.|.:|..:|::   ||
  Fly  1458 LDPSH-------------------------------------------RGTGDEHIHTLM---EF 1476

  Fly   970 ALNLLRILRDIRSKGIFFEKD-SKLTGSLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTS 1033
            ::.:..::.       .|.|| .:....|:||:..|.|.|||:|.||.:|||||..||:||||.|
  Fly  1477 SIAMQEVVD-------AFNKDLLEFNLILRIGMNIGDVTAGVIGTSKLYYDIWGDAVNVASRMDS 1534

  Fly  1034 TGVRDGIHVTESTANVLRDFNIRCTY--RGMTFVKGVGQVPTYL--------VDLDENLHFQQHS 1088
            ||:.:.|.|.:.....|.:   |..:  ||..:|||...:..:|        :|.||....:|..
  Fly  1535 TGLPNRIQVGKDCLPFLTN---RYEFEPRGSVYVKGKDHMEVFLYTTRRDNPLDDDEADKVEQLG 1596

  Fly  1089 PDNDSHKG 1096
            .....|:|
  Fly  1597 TKKMEHEG 1604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	106/389 (27%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	66/159 (42%)
		AcyC	681..1076	CDD:441717	121/488 (25%)
		Nucleotidyl_cyc_III	841..1076	CDD:448371	74/253 (29%)
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	76/217 (35%)
		PHA03307	836..>1015	CDD:223039	11/178 (6%)
		Guanylate_cyc	1388..1575	CDD:425528	73/243 (30%)