Protein Alignment CG32301 and rut

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Alignment Length: 1348
• Identity: 332/1348 - (24%)
• Similarity: 503/1348 - (37%)
• Gaps: 469/1348 - (34%)

  Fly    26 LRYKCRELRLEGVYHRHCHLVSVALVTQLIIVIEILMLIHVI--------LLF---SVVKNIDFL 79
            ||::..|  ||.:|.|:      .|..|...|:.::.|:.|:        |.|   :...||...
  Fly    16 LRFENDE--LECLYQRY------TLKLQRFSVLGVVALVFVLCGVMAALSLTFNNAATFHNIFNA 72

  Fly    80 TVLPYFAV--MLLTPSILMPSREPNVEQYESIAILVSCLMALLLTAMDLILPICYFRPFSLVPSY 142
            .|...|||  :||..|::.....|.:           |...||.||     .||...    :|:.
  Fly    73 IVCGLFAVVLVLLQCSVIKDHHLPTL-----------CYGILLFTA-----SICVVS----MPTL 117

  Fly   143 DHV------------------VIVLIYLMFPIAFVKNGRAYFLGLAVSLFYFGYMALIDKISTLD 189
            ..|                  |:.|.|.|.|:
  Fly   118 GSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPL--------------------------------- 149

  Fly   190 KVWELTAYG-----------AYLFFLNMLCMFLSRFQEYNM------------------------ 219
            ::||..|:|           .|..|.:.|     |:.|||.
  Fly   150 QIWEAVAFGIALPSVHISLTVYKIFTDAL-----RYLEYNQLIANIVIFIGVNVAGLVVNIMMER 209

  Fly   220 ---------RSGILSRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLM 275
                     |:.|.||.::..:|      .|.|:.|| |::|..:|..:::.|          |.
  Fly   210 AQRRTFLDTRNCIASRLEIQDEN------EKLERLLL-SVLPQHVAMQMKNDI----------LS 257

  Fly   276 PFTKTRH-LFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFL 339
            |.....| ::::.|..||||.||:|.||.|::.....:||.:|:|||..||..|:.|...|||.|
  Fly   258 PVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKIL 322

  Fly   340 GDSYTCVTGIPSYFPTHANACVNQALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQ 404
            ||.|.||:|:|.....||...|...||||:....|.:..:..:::|:|:|:|.:|.|::||.|||
  Fly   323 GDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQ 387

  Fly   405 FDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNHYVYE-------------EGTDTAKLDPLL 456
            ||:||.||.:.|.:||.|.||.||::..||..|...|..|             .|.||..:.|..
  Fly   388 FDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPP 452

  Fly   457 QRSN---LSTYLIRS-----RLPNFEDTDDLEDDNFSLNDYRFS--FSFSQ-------------- 497
            .|..   |:|..:||     |..:|.:..::...  .|:..:||  ..||.
  Fly   453 HRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQ--LLHTIKFSEPVPFSNIATGSFPSAASALG 515

  Fly   498 ------------------------DYEDIQV--KAQRDMI------------------------- 511
                                    :..::||  |..|.:|
  Fly   516 GGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGG 580

  Fly   512 ------------------------LEVEHMPVNRVQTC-------------------KIRRPM-- 531
                                    :.|...|.:...|.                   |.:||.
  Fly   581 GVDSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRK 645

  Fly   532 -HRIA--KEDINEEYRF----------------HLESYYLFTTFRSWRMEWSFNKMRDLLMKYSL 577
             |.:|  .:..|...||                |::.  |...||...||..::|      .:.|
  Fly   646 RHSVAAHHQPTNRVNRFLSQAINARSVDCDKSEHVDR--LTLRFRQSDMEREYHK------DFDL 702

  Fly   578 GMMVFAGATIIAMDLLVKSEAMDYTML---FSLFLLILLPLLLASYKKLWLRGRRLSPITQPTFF 639
            |.....|.:::   ||:...|:..|.|   ..|.||.|...:..|...:.|...||
  Fly   703 GFTTAMGCSLL---LLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRL--------- 755

  Fly   640 LSRWFIKASDLIEKSVFVRIPLAIMVLFLLYVMSSETVFSC----DIARLELEIINSELHNLRPQ 700
              :|.|..   |.:|..:|:.:.|..:.|:|.:....||:|    ..:........::.|.
  Fly   756 --KWIIWD---ISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGNGTTSFQNDSHR---- 811

  Fly   701 MLCFMPWGVTYAVVIVLSLMLVIIGIPLIIKLGVGLAILGSHVITVHAYYGFAFERSQTTNI--- 762
             .|.:|..|:.:.......:.|.:.:|:|.|   .|.:||...|     ||...|.|. .||
  Fly   812 -KCSLPQYVSLSAAFAFLSVSVFLRLPIIFK---SLLVLGMGTI-----YGLFIELSH-QNIFEC 866

  Fly   763 ---GVTSSL-AH--SWYMVAFFIVVVVREG-------YLNYI--LKASYFMSMCFEKKHELTKVK 812
               .|.:|: .|  |...:|.|::.::..|       .|:::  |:||       ::|.|: .|.
  Fly   867 YDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQAS-------QEKKEM-DVL 923

  Fly   813 TRTIKIIMANILPTHVAEVF--KVRRRSDQLYYENFSQVAVMFATIENY-----EADKSG----- 865
            ..:.|.|:.|:||.|||..|  ...|.:.:||::::::|.|:||::.|:     |.|.|.
  Fly   924 QESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLEC 988

  Fly   866 LRALHEMICYFDELLVNYQSWYKIEKIKVMGWTYLAACGLHVDHYTDFSVSVPISTNRESDKLQK 930
            ||.|:|:|..||||| ....:..|:|||.:|.||:|..|| :..|                |:|
  Fly   989 LRLLNEIIADFDELL-KEDRFRGIDKIKTVGSTYMAVVGL-IPEY----------------KIQ- 1034

  Fly   931 SGSVRFAPMDGDEIMIKDLHPTQATTNEDDNTILVMTEFALNLLRILRDIRSKGIFFEKDSKLTG 995
                   |.|.:.:.   .|.|            .:.|:...:...|::|.|       .|....
  Fly  1035 -------PNDPNSVR---RHMT------------ALIEYVKAMRHSLQEINS-------HSYNNF 1070

  Fly   996 SLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANVL--RDFNIRCT 1058
            .|::||..|||:|||:|..||.|||||:|||:||||.||||.....||:...:.|  ..|..||
  Fly  1071 MLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRC- 1134

  Fly  1059 YRGMTFVKGVGQVPTYL----------------VDLDENLHFQQHSPD 1090
             ||...|||.|.:.||.                :.|.::|    |:||
  Fly  1135 -RGTIKVKGKGDMVTYFLCDSGNKSLNGEVRNAMSLPQSL----HAPD 1177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	127/482 (26%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	68/155 (44%)
		AcyC	681..1076	CDD:441717	126/442 (29%)
		Nucleotidyl_cyc_III	841..1076	CDD:448371	84/262 (32%)
rut	NP_511156.2	AC_N	<17..255	CDD:318454	60/310 (19%)
		Guanylate_cyc	266..428	CDD:425528	69/161 (43%)
		Adcy_cons_dom	624..698	CDD:461877	14/75 (19%)
		AcyC	742..1150	CDD:441717	140/493 (28%)
		Guanylate_cyc	954..1151	CDD:425528	84/246 (34%)