Protein Alignment CG32301 and Gucy2c

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_037302.1
• Gene: Gucy2c / 25711
• RGDID: 2771
• Length: 1072
• Species: Rattus norvegicus
• Alignment Length: 321
• Identity: 89/321 - (27%)
• Similarity: 146/321 - (45%)
• Gaps: 71/321 - (22%)

  Fly   254 TLARSLQ--DAIASHIEEDPSNLMPFTKTR--HL-FM----------------EP--HPEVSILE 295
            ||.|.||  .....|:.|:.:.|....:.|  || ||                ||  :.||:|..
  Rat   762 TLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLVVKSLKEKGIVEPELYEEVTIYF 826

  Fly   296 ADMVDFTGL---TTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPT-H 356
            :|:|.||.:   :|.|||.|:   |::::.|||...:|:...:::.:||:|...:|:|..... |
  Rat   827 SDIVGFTTICKYSTPMEVVDM---LNDIYKSFDQIVDHHDVYKVETIGDAYVVASGLPMRNGNRH 888

  Fly   357 ANACVNQALDMIEI--SREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLE 419
            |......|||::..  :.|:.......:.:|||||||...||::|:...::.::...|:..:|:|
  Rat   889 AVDISKMALDILSFMGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRME 953

  Fly   420 SSGLPGMVHISSRTLGLL---DNHYVYEEGTDTAKLDPLLQRSNLSTYLIRSRLPNFEDTDDLED 481
            |:|||..:|:||.|:.:|   |..::||...:|.    |..|...:||.:..          ::|
  Rat   954 STGLPLRIHMSSSTIAILRRTDCQFLYEVRGETY----LKGRGTETTYWLTG----------MKD 1004

  Fly   482 DNFSL-------NDYRFSFSFSQDYEDIQVKAQRDMILEVEHMPVNRVQTCKIRRPMHRIA 535
            ..::|       |..|....||            |||  |..:...:....|.|||. |:|
  Rat  1005 QEYNLPTPPTVENQQRLQTEFS------------DMI--VSALQKRQASGVKSRRPT-RVA 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	67/222 (30%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	55/183 (30%)
		AcyC	681..1076	CDD:441717
		Nucleotidyl_cyc_III	841..1076	CDD:448371
Gucy2c	NP_037302.1	Periplasmic_Binding_Protein_type1	34..414	CDD:471960
		Protein Kinases, catalytic domain	479..749	CDD:473864
		CYCc	787..978	CDD:214485	58/193 (30%)