DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32301 and Gucy2f

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_001007577.1	Gene:	Gucy2f / 245650	MGIID:	105119	Length:	1108	Species:	Mus musculus

Alignment Length:	240	Identity:	59/240 - (24%)
Similarity:	124/240 - (51%)	Gaps:	33/240 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 NMLCMFLSRFQEY--NMRSGILSRYQVVYQNLVFQMAMKEEKA--LLDSIIPVTLARSLQDAIAS 265
            |::...|...::|  |:...|..|.:        ::.::::|.  ||..::|:::|.||:....
Mouse   819 NIIDSMLRMLEQYSSNLEDLIRERTE--------ELEIEKQKTEKLLTQMLPLSVAESLKKGCT- 874

  Fly   266 HIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANH 330
             :|.:..:|                |::..:|:|.||.::...|..::|.:|::|:..||.....
Mouse   875 -VEPEGFDL----------------VTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGS 922

  Fly   331 NRATRIKFLGDSYTCVTGIPSYFPT-HANACVNQALDMIEISREVSKRRNKKID--LRIGVHSGE 392
            :...:::.:||:|...:|:|....: ||....|.:||::........|...::.  :|||:|||.
Mouse   923 HDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGP 987

  Fly   393 ILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTLGLL 437
            ::||::|||..::.::...|:..:|:||:|||..:|:|..|:.:|
Mouse   988 VVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTIL 1032

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	44/158 (28%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Gucy2f	NP_001007577.1	PBP1_sensory_GC_DEF-like	54..435	CDD:380594
		PKc_like	545..815	CDD:419665
		HNOBA	<824..869	CDD:400168	10/52 (19%)
		CYCc	848..1040	CDD:214485	53/203 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900