DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32301 and Npr2

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_776149.1	Gene:	Npr2 / 230103	MGIID:	97372	Length:	1047	Species:	Mus musculus

Alignment Length:	311	Identity:	77/311 - (24%)
Similarity:	136/311 - (43%)	Gaps:	71/311 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 VKNG-RAYFLGLAVSLFYFGYMALIDK-------ISTLDKVW-----ELTAYGAYLFFL------ 204
            |:|| |.||            ...||:       :..:::.|     |...:|....|:
Mouse   740 VRNGQRPYF------------RPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKE 792

  Fly   205 ---NMLCMFLSRFQEY--NMRSGILSRYQVVYQNLVFQMAMKEEK----ALLDSIIPVTLARSLQ 260
               ::|...|.|.::|  |:...:..|.|          |..|||    |||..|:|.::|..|:
Mouse   793 GGTSILDNLLLRMEQYANNLEKLVEERTQ----------AYLEEKRKAEALLYQILPHSVAEQLK 847

  Fly   261 DAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFD 325
                              :...:..|....|:|..:|:|.||.|:.......:|.:|::|:..||
Mouse   848 ------------------RGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFD 894

  Fly   326 LAANHNRATRIKFLGDSYTCVTGIPS-YFPTHANACVNQALDMIEI--SREVSKRRNKKIDLRIG 387
            ...::....:::.:||:|..|:|:|. ....||......||.:::.  |..:..|.:.::.||||
Mouse   895 AIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIG 959

  Fly   388 VHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLD 438
            ||:|.:.||::||...::.::...|:..:|:||:|....:|:||.|...||
Mouse   960 VHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALD 1010

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	47/159 (30%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Npr2	NP_776149.1	PBP1_NPR_B	26..421	CDD:380607
		PK_GC-A_B	518..792	CDD:270944	12/63 (19%)
		HNOBA	<798..846	CDD:369471	17/57 (30%)
		CYCc	825..1009	CDD:214485	55/201 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900