Protein Alignment CG32301 and gcy-34

DIOPT Version :9

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_506319.1
• Gene: gcy-34 / 191656
• WormBaseID: WBGene00001554
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 127/642 - (19%)
• Similarity: 223/642 - (34%)
• Gaps: 220/642 - (34%)

  Fly    28 YKCRE-----LRLE------GVYHRHCHLVS--VALVTQLIIVIEILMLI--------------- 64
            ::|.|     |.|.      |:|    |:|.  |..|.:|:..::|.:::
 Worm   122 FRCEENPDGTLMLHYFTGRPGLY----HIVKGVVKEVAKLVFNLDISLVVQGRTQRSVHMNNGER 182

  Fly    65 ---HVILLFSVVKNI-----------------------------------DFLTVLPYFAVM--- 88
               |||.|   :||:                                   ||...|||..|:
 Worm   183 VEEHVIFL---IKNVEEPRRDSDTSTTSALTSVEPDFGEIIDDNLKVSLQDFSRALPYHFVLDES 244

  Fly    89 -----------------LLTPSI----LMPSREPNVE-QYESIAILVSCLMALLLTAMDL----- 126
                             ||.|..    :.....|.:. .:|:|...::.:..|.:....|
 Worm   245 CRLVQCGDELYNHIPNELLQPGTPILRIFEINRPQIPLDFENICNFINAVFVLQVKTSPLRKKHM 309

  Fly   127 -----------------------ILPICYFR---PFSLVPSYDHVVIVLIYLMFPIAFVKNGRAY 165
                                   :...|:.:   ...::.:..|:    |||..|.....|
 Worm   310 NAMTKEEREQEVEAMEEEVESNELTQGCHLKLKGQMMMLSTKKHI----IYLCSPYVTSIN---- 366

  Fly   166 FLGLAVSLFYFGY----MALIDKISTLDKVWELTAYGAYLFFLNMLCMFLSRFQ--EYNMRSGIL 224
                  .|..||.    |.|.|  :|.|           |..||.     .|..  |.|::   |
 Worm   367 ------ELMQFGMRLTAMPLHD--ATRD-----------LILLNQ-----QRLSDVEVNLQ---L 404

  Fly   225 SRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLFMEP-H 288
            .......:.:..::.::.:|.  |||:...|.|.:...:.|              ..||  || .
 Worm   405 EANNEQLETMTHELEVERQKT--DSILKDMLPRKIAKQLLS--------------GEHL--EPCE 451

  Fly   289 PEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYF 353
            .|.:::..|:..|..:....:..::|.:|:|:|...|.........:::.:.|||..|:|||.|.
 Worm   452 YEATVMFCDLPAFQQIIPVCQPKNIVKLLNEVFFKLDRIVVLRGVYKVETVSDSYMTVSGIPDYT 516

  Fly   354 PTHANACVNQALDMIEISREVSKRRNK-KIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNR 417
            ..||....:.||.|:..:|.|....|| ...||||:|||.|:||::|....::.::.:.|.:.::
 Worm   517 SEHAENMCHVALGMMWEARSVMDPVNKTPFLLRIGLHSGTIIAGVVGTKMPRYCLFGETVTLASQ 581

  Fly   418 LESSGLPGMVHISSRTLGLLDNHYVYEEGTDTAKLD-------PLLQRSNLSTYLIRSRLPN--F 473
            :||.|:.|.:..||         :.|.:..:|.:.:       .:..|.::.||.:...|..  :
 Worm   582 MESLGVAGKIQCSS---------WTYSKAMETGRFEFSPRGRINVKGRGDVETYFLMRSLKKSIW 637

  Fly   474 EDTDDLEDDNFSLNDYRFSFSFSQDYEDIQVKAQRDMILEVEHMP---VNRVQTCKI 527
            |.||...|.|  :|..       :.||::::..:....::.:..|   .|...||.|
 Worm   638 EITDHERDVN--VNSI-------EGYEELEIFIENAQTVKHDGHPKANQNHSATCTI 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	46/157 (29%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
gcy-34	NP_506319.1	HNOB	3..167	CDD:285002	12/48 (25%)
		HNOBA	224..441	CDD:285003	42/253 (17%)
		CYCc	421..609	CDD:214485	56/214 (26%)
		Guanylate_cyc	453..629	CDD:278633	48/184 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900