DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32301 and gcy-19

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_001348702.1	Gene:	gcy-19 / 191650	WormBaseID:	WBGene00001544	Length:	1187	Species:	Caenorhabditis elegans

Alignment Length:	266	Identity:	64/266 - (24%)
Similarity:	134/266 - (50%)	Gaps:	31/266 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 YNMRSGILSRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTR 281
            :|:.....:..:|..::...::..:::||      .|.|.|.|...:|..:::..:
Worm   853 FNILEDYTTNLEVEVEDRTKELTAEKKKA------DVLLGRMLPKQVAERLKQGQT--------- 902

  Fly   282 HLFMEPH--PEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYT 344
               :||.  ..|::..:|:|.||.|........:|.:|::|:.:||.....:...:::.:||.|.
Worm   903 ---VEPEGFDSVTVFFSDVVKFTQLAAKCSPFQVVNLLNDLYSNFDAIIEEHGCYKVESIGDGYL 964

  Fly   345 CVTGIPSYFPTHANACVNQ----ALDMIEI--SREVSKRRNKKIDLRIGVHSGEILAGIIGLTKW 403
            ||:|:||   .:.||.:.|    :||.:..  |.::.....:|::|||||:||..:||::||:..
Worm   965 CVSGLPS---KNGNAHIKQIVELSLDFMSYCKSFKIPHLPREKVELRIGVNSGPCVAGVVGLSMP 1026

  Fly   404 QFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNHYVYEEGTDTAKLDPLLQ-RSNLSTYLIR 467
            ::.::...|:..:|:||:|....:|:|:.:..||..||..:..| .::.|.::: :..:.|:.:.
Worm  1027 RYCLFGDTVNTASRMESNGKASHIHLSAASYTLLMKHYPNQYNT-ASRGDVIIKGKGVMETFWVF 1090

  Fly   468 SRLPNF 473
            .|...|
Worm  1091 ERNNQF 1096

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	48/163 (29%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
gcy-19	NP_001348702.1	PBP1_NPR_GC_like	45..467	CDD:107347
		PKc_like	571..841	CDD:328722
		CYCc	876..1065	CDD:214485	56/209 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900