DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32301 and gcy-6

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_001294696.1	Gene:	gcy-6 / 191644	WormBaseID:	WBGene00001533	Length:	1086	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	51/215 - (23%)
Similarity:	102/215 - (47%)	Gaps:	25/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 LLDSIIPV--TLARSLQDAIASHI-----EEDPSNLMPF-------TKTRHLFMEPHPE----VS 292
            |:|.:..|  :.|.:|:|.:|..:     |:..|:::.:       .....|.....||    |:
Worm   830 LMDHVFNVLESYASTLEDEVAERMKELVEEKKKSDVLLYRMLPRQVADKLKLGQTVEPETFDIVT 894

  Fly   293 ILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIP-----SY 352
            :..:|:|.||.|........:|.:|:.|:..||.....:...:::.:||.|...:|:|     .:
Worm   895 LFFSDVVSFTTLAGKCTPLQVVNLLNGLYTIFDGIIEQHDVYKVETIGDGYFVASGVPRRNGNEH 959

  Fly   353 FPTHANACVNQALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNR 417
            ....|:..:|....:.:.|  :.....:||.:|:|.|.|.::||::|||..::.::...|:..:|
Worm   960 TRNIASMSINFVKSLADFS--IPHLPGEKIKIRVGFHCGSVVAGVVGLTMPRYCLFGDAVNTASR 1022

  Fly   418 LESSGLPGMVHISSRTLGLL 437
            :||:..||.:|:|.....:|
Worm  1023 MESNSKPGQIHLSEEANQML 1042

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	42/164 (26%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
gcy-6	NP_001294696.1	PBP1_NPR_GC_like	29..445	CDD:107347
		ANF_receptor	57..424	CDD:279440
		PKc_like	585..822	CDD:304357
		HNOBA	<847..879	CDD:285003	4/31 (13%)
		CYCc	858..1048	CDD:214485	44/187 (24%)
		Guanylate_cyc	885..1070	CDD:278633	41/160 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000