DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32301 and gcy-11

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_001359843.1	Gene:	gcy-11 / 181745	WormBaseID:	WBGene00001537	Length:	1168	Species:	Caenorhabditis elegans

Alignment Length:	349	Identity:	83/349 - (23%)
Similarity:	162/349 - (46%)	Gaps:	67/349 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 STLDKVW-ELTAYGAYLFFLNMLCMFLSRFQEYNMRSGI---LSRYQVVYQNLV------FQMAM 240
            |.::|.| |..|....:..:..|...||:..:.|:...|   |.||:...::::      .:...
Worm   861 SVVEKCWVEDPASRPSIKKVRELLKPLSKGLKGNIADNIMNLLDRYRNNLEDVIKERTEQLEDER 925

  Fly   241 KEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLT 305
            |..::||..::|.::|.||::.                  :.:..|.:..|||..:|:|.||.|:
Worm   926 KRNESLLLQLLPKSVANSLKNG------------------QPVDAEFYDSVSIYFSDIVGFTALS 972

  Fly   306 TTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIP---SYFPTHANACVNQALDM 367
            :......:|.:|:.|:.:||...:.....:::.:||:|..|:|:|   ||.  ||....:.:|::
Worm   973 SKSTPLQVVNMLNNLYTNFDTIIDKFDCYKVETIGDAYMFVSGLPEVNSYL--HAGEVASASLEL 1035

  Fly   368 IEISR--EVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHIS 430
            ::..:  .||...::|:.||||.|:|.::.|::|:...::.::...|.|.|.:||||.|..:.||
Worm  1036 LDSIKTFTVSHCPDEKLRLRIGNHTGPVVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQIS 1100

  Fly   431 SRTLGLL--DNHYVYEEGTDTAKLDPLLQRSNLSTYLIRSRLPNFEDTDDLEDDNFSLNDYRFSF 493
            |....|:  ...||.|            ||..:   :::::         ||...:.:|||
Worm  1101 SDAYELILKCGGYVTE------------QREKI---VLKNK---------LEVMTYWMNDY---- 1137

  Fly   494 SFSQDYEDIQVKAQRDMILEVEHM 517
              |:|....::.|.::....:||:
Worm  1138 --SKDARLARLVAHQEKFPHLEHL 1159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	48/162 (30%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
gcy-11	NP_001359843.1	Periplasmic_Binding_Protein_type1	<234..452	CDD:385651
		PKc_like	640..890	CDD:389743	8/28 (29%)
		CYCc	923..1116	CDD:214485	57/212 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900