Protein Alignment CG32301 and acy-3

DIOPT Version :9

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_497765.4
• Gene: acy-3 / 175489
• WormBaseID: WBGene00000070
• Length: 1243
• Species: Caenorhabditis elegans
• Alignment Length: 1140
• Identity: 206/1140 - (18%)
• Similarity: 410/1140 - (35%)
• Gaps: 296/1140 - (25%)

  Fly    13 RSLGNMPGYEWKLLRYKCRELRLEGVYHRHCHLVSVALVTQLIIVIE-ILMLIHV-----ILLFS 71
            |:||::||:                          .||.|.:|:::. :.::.|:     |..|.
 Worm    38 RTLGHIPGF--------------------------YALWTAVILLLSTVTIIFHILRPARIAAFQ 76

  Fly    72 VVKNIDFLTVLPYFAVMLLTPSILMPSREPNVEQYESIAILVSCLMALLLTAMDLILPICYFRPF 136
            ::..|          |:||..:..:|.       |||   |...|:|:                |
 Worm    77 ILAGI----------VLLLDVAFALPG-------YES---LFPALLAV----------------F 105

  Fly   137 SLVPSYDHVVIVLIYLMFPIAFVKNGRAYFLGLAVSLFY-----FGYMALIDKISTLDKVWELTA 196
            ||            |..|.:.|       :..||.|...     ..::..::.:.|.    ||.|
 Worm   106 SL------------YTFFSLPF-------YAILATSTLISIVQTCSFLLFVEPLHTN----ELLA 147

  Fly   197 YGAYLFFLNMLCMFLSRFQEYNMRSGILSRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARSLQD 261
            ......:.|...::|....:...|:..||...........:........||.|.:|..|....:.
 Worm   148 IIVVHIWTNFTGIYLCSTADRLARNAFLSARNSSEAESTAEFQSNRLNKLLSSFLPYHLINQARH 212

  Fly   262 AIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDL 326
            .|..:             ..||:.|.:.:||:....:|.|..:.......|...:|.||....:.
 Worm   213 QITLY-------------KPHLYNETYSQVSVAYGRLVGFESVLAQCSSIDAARVLKELDSRIER 264

  Fly   327 AANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVNQALDMIEISREVSKRRNKKIDLRIGVHSG 391
            .|..|..||:  ..:..|.|..||.....||......::::..:...........:.:.||:.||
 Worm   265 LAASNGCTRV--ASEGITAVCSIPGIDSQHATKLCRFSMELETLINSFRDATGADVSVCIGIDSG 327

  Fly   392 EILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNHYVYEEGTDTAKLDPLL 456
            .:.||::|::||.:|:.....|....::|:.....|::|:.|...|.:...:|           |
 Worm   328 PVTAGVVGVSKWHYDVIGSVFDNALLMQSNATEPGVYVSNETRRFLGSTGEFE-----------L 381

  Fly   457 QRSNLSTYLIRSRLPNFEDTDDLEDDNFSLNDYRFSFSFSQDYEDIQVKAQRDMILE--VEHMP- 518
            ::..:. :.:...||:        .:.|.:|. |||.        :.|....:.:|:  |...|
 Worm   382 EKCPIG-WKLYGHLPS--------PELFPVNK-RFSL--------VTVPQAVNRVLQSIVAMNPT 428

  Fly   519 VNRVQTCKIRRPMHRIAKEDINEEYRFHLESYYLFTT----FRSWRMEWSFNKMRDLLMKYSLGM 579
            :..:.|.|.|:......|.|:.::   .:|...:.:|    ||:..:|..::|..|.....||.:
 Worm   429 LKTMGTNKKRKGEKSQEKFDMQKK---KVEHSTIISTLSQRFRNPGLEAEYHKETDHWFIPSLAI 490

  Fly   580 MVFAGATIIAMDLLVKSEAMDYTMLFSLFLLILLPLLLASYKKLWLRGRRLSPITQPTFFLSR-- 642
            .:|                  :.:::.::.::::|.|:.|...:      :..:|...|.|..
 Worm   491 SIF------------------FLVVYGIYHMLVMPRLITSLALI------VGALTVMFFILLMLY 531

  Fly   643 --WFIKASDLIEKSVFVRIPLAIMVLFLLYVMSSETVFSCDIARLELEIINSELHNLRPQM---- 701
              :|...|..|.::........|:::.:|:|......|||                  ||.
 Worm   532 IDYFHTFSQFITRTSAGHAVSIILIIVILFVCGIVNTFSC------------------PQPNAPD 578

  Fly   702 LC---------FMPWGVTYAVVIVLSLMLVIIGIPLIIKLGVGLAILGSHVITVHAYYGFAFERS 757
            :|         |..|.:|.||.:  ....|.:.|.|||.|           :|    ||.....:
 Worm   579 VCQKAHFSTYSFAMWTITTAVFV--RFPSVYLAILLIISL-----------LT----YGLQIYVT 626

  Fly   758 QTTNIG---VTSSLAHSWYMVAFFIVVVVREGYLNYILKASYFMSMCFEKKHELTKVKTRTIKI- 818
            :....|   ..:.|..|.::::...:|.:.......:|:..:   :...|..|.|.:|.:.|.:
 Worm   627 RPDEFGPREFMTELDLSCFLISLVSMVFLHSRRCERLLRLDF---LAVVKGIEETSMKDKLINLN 688

  Fly   819 --IMANILPTHVAEVFKVRRRSDQLYYENFSQVAVMFATIENYEAD-KSGLRALHEMICYFDELL 880
              ::.|::|.|||.  .|.:::..:::.:...|.:.:..:..::.: ::|:..|:.:..:||:.:
 Worm   689 NQMLLNLVPAHVAP--GVIQKAGDVWHHSHQSVGIAYIAVSGFDLEGEAGINGLNYVFSHFDQAI 751

  Fly   881 VNYQSWYKIEKIKVMGWTYLAACGLHVDHYTDFSVSVPISTNRESDKLQKSGSVRFAPMDGDEIM 945
            .||:.   :||:|.....|:.|.||..|                     .:.:|...|....|:|
 Worm   752 ANYKG---VEKVKSANRFYIVAVGLLPD---------------------AAQNVNETPWTIGELM 792

  Fly   946 IKDLHPTQATTNEDDNTILVMTEFALNLLRILRDIRSKGIFFEKDSKLTGSLKIGIAHGPVMAGV 1010
            ....|           .|:.:::||:                |.:.    .::||:..|..:|.|
 Worm   793 STLAH-----------FIISISQFAM----------------ENEF----HVQIGVDCGSTLAFV 826

  Fly  1011 VGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANVLRDFNIRCTYRGMTFVKGVG--QVPT 1073
            ....:|.|:|:|.|::.:..:......|...|:|.....||...:|.:.:.:.....:.  ::.|
 Worm   827 ANTDQPRYEIFGETLDRSRTLMQAAGHDTTLVSEEVFLALRPRPLRFSSQPVKVAMNLNAYELVT 891

  Fly  1074 YLVDLDENLHFQQHSPDNDSHKGSIVSVHWLDEKR 1108
            .|.|:..::...... :.:.|...:|...:.::.|
 Worm   892 GLRDVSVDIPTMPRE-EQERHTQGMVEAQFANQSR 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	36/155 (23%)
		CYCc	812..1051	CDD:214485	45/242 (19%)
		Nucleotidyl_cyc_III	841..1076	CDD:299850	41/237 (17%)
acy-3	NP_497765.4	TctB	26..137	CDD:284693	32/179 (18%)
		CYCc	195..378	CDD:214485	43/197 (22%)
		Nucleotidyl_cyc_III	221..382	CDD:299850	37/173 (21%)
		CYCc	696..873	CDD:214485	44/233 (19%)
		Nucleotidyl_cyc_III	711..880	CDD:299850	40/223 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900