Protein Alignment CG32301 and Ac13E

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: XP_061516135.1
• Gene: Ac13E / 1272181
• VectorBaseID: AGAMI1_002114
• Length: 1689
• Species: Anopheles gambiae
• Alignment Length: 1688
• Identity: 313/1688 - (18%)
• Similarity: 485/1688 - (28%)
• Gaps: 813/1688 - (48%)

  Fly    38 VYHRHCHLVSVALVTQLIIVIEILMLIHVILLFSVVKNIDFLTVLPYFAVMLLTPSILMPSREPN 102
            :|..|.||:|.....             ::.|||:             .::|||...|.|
Mosquito   148 LYRAHTHLLSSCCAV-------------LLCLFSL-------------CLLLLTREALSP----- 181

  Fly   103 VEQYESIAILVSCLMALLLTAMDLILPICYFRPFSLVPSYDHVVIVLIYL--------------- 152
               ....:|.:..:| |:.|.:.|.|.:|    .::..:|.....||.:|
Mosquito   182 ---LGHFSICIEIVM-LIYTIIPLPLWLC----CTITMAYSVCFEVLSFLHQTHYDYNSRPGGQP 238

  Fly   153 -MFPIAFVKNGRAYFLGLAVSLF-----------------------YFGYMALIDKISTLDKVWE 193
             :.|:|......|..|...|::.                       .|.|..::.::
Mosquito   239 TVSPLAAGITTAARLLAEEVAIAGSDQQQQHHHHQHHHHHHHQTGDSFVYKIVLIRV-------- 295

  Fly   194 LTAYGAYLFFLNMLCMFLSRFQEYNMRSGILSRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARS 258
            |.....:|..:.:|.|.:.|.:...|:.|         |||:.:..::.||.|.:.:|...:...
Mosquito   296 LIQLCVHLIGIQILIMTVVRMRGTFMKVG---------QNLLVRRQLEMEKQLKEKMIHSMMPPK 351

  Fly   259 LQDAIASHIEED---------------------PSNLMPFTKTRHLFMEPHPEVSILEADMVDFT 302
            :.|.:   ::|.                     ||:|....:..|  |.....||||.||:|.||
Mosquito   352 VADLL---LKESGSVPKGTSFDQYPAPGGRRTTPSDLKSLFRPFH--MNRMENVSILFADIVGFT 411

  Fly   303 GLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVNQALDM 367
            .:::|.....||.||::||..||.....|...:|..|||.|.||:|.|...|.||..||...|.|
Mosquito   412 RMSSTKTAEQLVEILNDLFERFDDLCLVNGCEKISTLGDCYYCVSGCPEPRPDHAICCVEMGLGM 476

  Fly   368 IEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSR 432
            ||..|....:||:.|.:|:|||:|.:|.||:|..:.:||:||.||.:.||:||||.|..||:|..
Mosquito   477 IESIRVFDAQRNEGIKMRVGVHTGTVLCGIVGTKRVKFDVWSNDVTLANRMESSGKPDQVHVSEE 541

  Fly   433 TLGLLDNHYVYEEGTDT----------------------------------------AKLDPL-- 455
            |.|.|.:.|:.|||.:.                                        :.||.|
Mosquito   542 TCGFLGDSYIIEEGEEVDGHRTYFVLGKRLDLVGSITEGLSSIGLPVDLNLLGASSPSPLDELRD 606

  Fly   456 ------------LQRS--NLS--------------------------------------TYLIRS 468
                        |.||  |||                                      |..:||
Mosquito   607 YATSEEHPESSCLSRSATNLSSIQPAVPPASPAGPVFFSSLHASPVSTPRPRIASLTKMTKFLRS 671

  Fly   469 ---------------RLP--------------------NFEDTDDLEDDN--------------- 483
                           |.|                    |..|:||.:||.
Mosquito   672 AVSKGDGGGRLLNAGRTPPAPPPVVEKPKIIISTKSISNGFDSDDDDDDRGGGGGCNEDDELVGM 736

  Fly   484 ----------------------------FSLNDYR------------------------------ 490
                                        ..||:.|
Mosquito   737 GGGAGRGRARSPASPRQSMTQEAPPTTLAMLNERRKQEGGGEAGVGQRKPPGRVLKVGAPEPDCG 801

  Fly   491 ------------------------FSFSFSQD-----YEDIQV---------------------- 504
                                    .|.|.:|:     |:.:.:
Mosquito   802 RICDSSKSCDDDVPCIERMGSSSSNSASNNQNITNGCYQHVPIVIVTPRPSCHTLDVANGGTPAP 866

  Fly   505 ------------KAQR----------------------DMILEV--------------------- 514
                        .|.|                      |.|::|
Mosquito   867 PASGAPTASGSCSAARSRDCGKGPTVGENPHASQGSVFDEIIDVRSYISQSRSDISPFARTGSYR 931

  Fly   515 -----------------------------------------------EHMPVNRVQTC------- 525
                                                           :|:....|..|
Mosquito   932 SQADRSSIIHEIALSAGAPGGSNSGTFGRPRSSTITTTHHHTCSEAHQHVRHGSVVVCPSSSRLL 996

  Fly   526 -------------------------------------KIRRPMHRIA------------------ 535
                                                 .:...:||::
Mosquito   997 GADGASLSPSATSRKDSGIRSNSRRSSIQHQLMLMSQTVALSVHRVSGYFTSSQSSLSGAIVTSA 1061

  Fly   536 -----------------------------------------KE-----------DINEEYRFHL- 547
                                                     ||           .:.::....|
Mosquito  1062 AGVPRAHKPNGSMRAGTIATAANSGGAAAAAAPGSRCCMGLKEPHPDPLAACLQQLRKQSDLQLI 1126

  Fly   548 ----------ESYY-------LFTTFRSWRMEWSFNKMR--------DLL----------MKYS- 576
                      .||.       :...|:|..||..|....        |||          .||:
Mosquito  1127 RCVRDNARSQRSYLVKPPLLPISLRFKSRPMEQEFRSKAHRFGSEGGDLLEGGSPPTLATPKYNT 1191

  Fly   577 -----LGMMVFAGATIIAMDLLVKSEAMD----YTMLFSLFLLILLPLLLASYKKLWLRGRRLSP 632
                 :..:|:. ||..::.||..|..::    :..:|..|..:.|..|....|::..|.|:
Mosquito  1192 YIDMLVSFVVYL-ATSTSLFLLSPSVYLESYKVWVCIFVFFSTVQLFALFICTKQVCRRTRK--- 1252

  Fly   633 ITQPTFFLSR--------------------WFIKASDLIEKSVF-VRIPLAIMVL---------- 666
               ||...||                    |.|....|:...|. :....|:|.:
Mosquito  1253 ---PTVRRSRPVATRSCYDCLLQLASAWYPWHICGGILMSLPVISILSNFAMMDVTKFRVFEFHY 1314

  Fly   667 -FLLYVMSSETVFSCDIARLELEIINSELHNLRPQMLCFMPWGVTYAVVIVLSLMLVIIGIPLII 730
             ||:|:.   .|..|:..:|.                    |.:..|:..:.|...|.|.:..::
Mosquito  1315 GFLMYIC---IVHFCNFTQLN--------------------WWMRNAMACITSAAFVGIAVGHMV 1356

  Fly   731 KL-----------GVGLAILGSHVITVHAYYGFA---------FERSQTTNIGVTSSLAHSW--- 772
            :|           ....|.||::...:.|..|..         ..|:|           ..|
Mosquito  1357 ELQALEVATAAAAAAAAATLGANGTALLAAGGGGGDGAGGNEMLHRAQ-----------FDWFNN 1410

  Fly   773 YMVAFFI---VVVVREGYLNYILKASYFMSMCFEKKHELTKVKTRTIK----IIMANILPTHVAE 830
            |.|..::   :::|...:||...:..|.:|..........|::.:.:|    :::.||:|.||||
Mosquito  1411 YRVEIYVDLLLLLVLVWFLNREFEIGYRLSFHGSAVANQDKIRVQNMKNQADMLLHNIIPKHVAE 1475

  Fly   831 VFKVRRRSDQLYYENFSQVAVMFATI--------ENYEADKSGLRALHEMICYFDELLVNYQSWY 887
            ..|    :...|.||...:.::||:|        |:|...|..||.|:|:|..|||||.. ..:.
Mosquito  1476 QLK----NTAKYSENHHNIGIIFASIVNFNEMYDESYLGGKEYLRVLNELIGDFDELLAR-PEFR 1535

  Fly   888 KIEKIKVMGWTYLAACGLHVDHYTDFSVSVPISTNRESDKLQKSGSVRFAPMDGDEIMIKDLHPT 952
            .:||||.:|.|::||.||.           |.|
Mosquito  1536 CVEKIKTIGSTFMAASGLD-----------PSS-------------------------------- 1557

  Fly   953 QATTNEDDNTILVMTEFALNLLRILRDIRSKGIFFEKD-SKLTGSLKIGIAHGPVMAGVVGLSKP 1016
            :..|.|...|:|   :|||.:.:::..       |.:| .:....:::|...|.|.|||:|.||.
Mosquito  1558 RGETYEHLYTLL---DFALAMQQVVES-------FNRDLLEFNLIMRVGYNFGDVTAGVIGTSKL 1612

  Fly  1017 HYDIWGHTVNMASRMTSTGVRDGIHVTESTANVL---RDFNIRCTYRGMTFVKGVGQVPTYLV 1076
            :|||||..||:||||.||||...:.|......||   .||.    .||..:|||...:..||:
Mosquito  1613 YYDIWGDAVNVASRMDSTGVAGRVQVGADCIPVLGERYDFQ----PRGKVYVKGKDHMEVYLL 1671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	117/453 (26%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	70/155 (45%)
		AcyC	681..1076	CDD:441717	107/436 (25%)
		Nucleotidyl_cyc_III	841..1076	CDD:448371	75/246 (30%)
Ac13E	XP_061516135.1	None