Protein Alignment CG32301 and Adcy9

DIOPT Version :9

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: XP_011244107.1
• Gene: Adcy9 / 11515
• MGIID: 108450
• Length: 1372
• Species: Mus musculus
• Alignment Length: 1289
• Identity: 313/1289 - (24%)
• Similarity: 501/1289 - (38%)
• Gaps: 402/1289 - (31%)

  Fly    68 LLFSVVKNIDFLTVLPYFAVMLLTPSILMPSREPNVEQYESIAILVSCL---------------- 116
            ||:|:           ||||.:.:..|:|        ...::..||.|:
Mouse   128 LLWSI-----------YFAVHMKSKVIVM--------VVPALCFLVVCVGFFLFTFTKLYARHYA 173

  Fly   117 -----MALLLTAMDLILPICYFRPFS-LVPSYDH------------------VVIVLIYLMFPIA 157
                 :.||:.|:.|......:.|.| .|.|.:|                  :.|.::.|::.:.
Mouse   174 WTSLALTLLVFALTLAAQFQVWTPLSGRVDSSNHTLTATPADTCLSQVGSFSICIEVLLLLYTVM 238

  Fly   158 FVKNGRAYFLGLAVSLFY--FGYM-------------ALIDKISTLDKVWELT----------AY 197
            .:....:.|||:..|:.:  |||.             ||         .|||.          |.
Mouse   239 QLPLYLSLFLGVVYSVLFETFGYHFRNEDCYPSPGPGAL---------HWELLSRALLHVCIHAI 294

  Fly   198 GAYLFFLNMLCMFLSRFQEYNMRSGILSRYQVVY--QNLVFQMAMKEEKALLDSIIPVTLARSL- 259
            |.:||.::          :...||..|...|.:.  ::|..:.|:||.  ::.|::|..:|..|
Mouse   295 GIHLFVMS----------QVRSRSTFLKVGQSIMHGKDLEVEKALKER--MIHSVMPRIIADDLM 347

  Fly   260 -------QDAIASHIEEDPSN-------------LMPFTKTRHLFMEPHPEVSILEADMVDFTGL 304
                   ::::..|....|.|             ..||.      |:...|||||.||:|.||.:
Mouse   348 KQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFK------MQQIEEVSILFADIVGFTKM 406

  Fly   305 TTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVNQALDMIE 369
            :.......||.:|::||..||......:..:|..|||.|.||.|.|.....||..|:...|.||:
Mouse   407 SANKSAHALVGLLNDLFGRFDRLCEQTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIK 471

  Fly   370 ISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTL 434
            ...:..:.:.:.:::|:|||:|.:|.||:|:.:::||:||.||::.|.:|..|:.|.||||..|.
Mouse   472 AIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATA 536

  Fly   435 GLLDNHYVYEEGTDTAKLDPLL---QRSNLSTYLIRSR-------------LPNFEDTDDLEDDN 483
            ..||:.|..|:|....:|...:   |...|.||||..:             |..||..||..:.:
Mouse   537 KYLDDRYEMEDGRVIERLGQSVVADQLKGLKTYLISGQRAKESHCSCAEALLSGFEVIDDSRESS 601

  Fly   484 ----------FSLNDY--------------RFSFSFS----------------QDYEDIQVKAQR 508
                      .|::|.              ....:|:                ||......|...
Mouse   602 GPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGTVQNGCQDEPKTSTKVTS 666

  Fly   509 DMILEV-----------------------------EHMPVNRVQTCKIRRPMHR----------- 533
            ..:|.:                             |.:..::...|:|.:...|
Mouse   667 SWLLFLSVPLLAHPPKASGGPNSKTQNGLLSPPAEEKLTNSQTSLCEILQEKGRWAGVSLDQSAL 731

  Fly   534 ------------------IAKED-INEEYRFHLESYYLFTTFRSWRMEWSF-NKMRDLLMKYSLG 578
                              :.||| :.::|.|..........|....:|.|: ...::.::|.| .
Mouse   732 LPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNS-P 795

  Fly   579 MMVFAGATIIAMDLLVKSEAMDYTMLFSLFLLILLPLLLASYKKLWLRGRRLSPITQPTFFLSRW 643
            :..||.||.        |..:|..:..::||::.:...| .|      |...:|  .|...|:
Mouse   796 VKTFASATF--------SSLLDVFLSTTVFLILSITCFL-KY------GATATP--PPPAALA-- 841

  Fly   644 FIKASDLIEK--SVFVRIPLAIMVLFLLYVMSSETVFSCDIARLE-------------------- 686
             :..:||:.:  |:.|.|.   ||.||      |.|.:|....||
Mouse   842 -VFGADLLLEVLSLIVSIR---MVFFL------EDVMTCTKWLLEWIAGWLPRHCIGAILVSLPA 896

  Fly   687 LEI---INSELH-NLRPQMLCFMPWGVTYAVV----------IVLSLMLVIIGIPLIIKLGVGLA 737
            |.:   |.||.. |:...|  |....|..|||          .:.|.:..|:|..|::.|.:.|.
Mouse   897 LAVYSHITSEFETNIHVTM--FTGSAVLVAVVHYCNFCQLSSWMRSSLATIVGAGLLLLLHISLC 959

  Fly   738 ILGSHVIT-VHAYYGFAFERSQTTNIGV------TSSLAHSWYMVAFFIVVVVREGYLNYILKAS 795
            ...|.|:: :.:...|:.:|: ..|..|      .:||.....::.||::::: ..:||...:.|
Mouse   960 QDSSIVMSPLDSAQNFSAQRN-PCNSSVLQDGRRPASLIGKELILTFFLLLLL-VWFLNREFEVS 1022

  Fly   796 YFMSMCFEKKHELTKVKTRTIK----IIMANILPTHVAEVFKVRRRSDQLYYENFSQVAVMFATI 856
            |.:....:.:.:|.:.|.::::    .::.||:|.||||..||    .|.|.:|.....|:||:|
Mouse  1023 YRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKV----SQTYSKNHDSGGVIFASI 1083

  Fly   857 --------ENYEADKSGLRALHEMICYFDELL--VNYQSWYKIEKIKVMGWTYLAACGLHVDHYT 911
                    ||||..|...|.|:|:|..|||||  .:|.|   |||||.:|.||:||.||:
Mouse  1084 VNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYNS---IEKIKTIGATYMAASGLN----- 1140

  Fly   912 DFSVSVPISTNRESDKLQKSGSVRFAPMDGDEIMIKDLHPTQATTNEDDNTILVMTEFALNLLRI 976
                         :.:.|:.|                 ||.:        .:.::.|||..::|:
Mouse  1141 -------------TAQCQEGG-----------------HPQE--------HLRILFEFAKEMMRV 1167

  Fly   977 LRDIRSKGIFFEKDSKLTGSLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIH 1041
            :.|..:..::|      ...|::|..|||:.|||:|.:|..|||||.|||:||||.:|||...|.
Mouse  1168 VDDFNNNMLWF------NFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQ 1226

  Fly  1042 VTESTANVLRDFNIRCTYRGMTFVKGVGQVPTYLV-DLDENLHFQQH----SPD 1090
            |:|.:..||........|||...|||.||:.|||. ...:|....||    |||
Mouse  1227 VSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGVVPQHQLSISPD 1280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	58/155 (37%)
		CYCc	812..1051	CDD:214485	84/252 (33%)
		Nucleotidyl_cyc_III	841..1076	CDD:299850	84/244 (34%)
Adcy9	XP_011244107.1	MFS	<134..260	CDD:391944	23/133 (17%)
		Guanylate_cyc	385..573	CDD:306677	70/193 (36%)
		Guanylate_cyc	1069..1260	CDD:306677	83/242 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900