DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32301 and Gucy2e

DIOPT Version :9

Sequence 1:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster
Sequence 2:	NP_570093.2	Gene:	Gucy2e / 113911	RGDID:	69322	Length:	1123	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	55/224 - (24%)
Similarity:	114/224 - (50%)	Gaps:	27/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 ILSRYQVVYQNLV------FQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTR 281
            :|.:|....:.||      .::..::.:.||..::|.::|.:|:  :.:.:|.
  Rat   836 MLEKYSQSLEGLVQERTEELELERRKTERLLSQMLPPSVAHALK--MGTTVEP------------ 886

  Fly   282 HLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCV 346
                |...:|:|..:|:|.||.::...|..::|..|::|:..||...:.:...:::.:||:|...
  Rat   887 ----EYFDQVTIYFSDIVGFTTISALSEPIEVVGFLNDLYTMFDAVLDSHDVYKVETIGDAYMVA 947

  Fly   347 TGIPSYFPT-HANACVNQALDMIEISREVSKRRNKKIDLRI--GVHSGEILAGIIGLTKWQFDIW 408
            :|:|..... ||....|.||:::..:.....|....:.:|:  |:|||..:||::|||..::.::
  Rat   948 SGLPRRNGNRHAAEIANMALEILSYAGNFRMRHAPDVPIRVRAGLHSGPCVAGVVGLTMPRYCLF 1012

  Fly   409 SKDVDITNRLESSGLPGMVHISSRTLGLL 437
            ...|:..:|:||:|||..:|:|..|:..|
  Rat  1013 GDTVNTASRMESTGLPYRIHVSRNTVQAL 1041

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	45/158 (28%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Gucy2e	NP_570093.2	PBP1_sensory_GC_DEF-like	71..445	CDD:380594
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	529..556
		PK_GC-2D	554..824	CDD:270945
		CYCc	861..1050	CDD:214485	51/199 (26%)
		Interaction with NCALD. /evidence=ECO:0000269\|PubMed:18178149	880..921		11/56 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900