Protein Alignment CG32301 and adcy7

DIOPT Version :10

• Sequence 1: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Sequence 2: NP_001106549.1
• Gene: adcy7 / 100127741
• XenbaseID: XB-GENE-1005225
• Length: 1061
• Species: Xenopus tropicalis
• Alignment Length: 1127
• Identity: 297/1127 - (26%)
• Similarity: 497/1127 - (44%)
• Gaps: 224/1127 - (19%)

  Fly    66 VILLFSVVKNIDFLTVLPYFAVMLLTPSILMPSREPNVEQYESIAILVSCLMALL---------- 120
            :||||.|..:...|.|| :|..          |:||    :..:|.:::..:||:
 Frog    36 LILLFVVGASCVTLIVL-FFTF----------SQEP----FRHLAFIITVFVALVVFCALYILVY 85

  Fly   121 --------LTAMDLILPIC-----YFRPF--SLVPSYDHVVIVL-----IYLMFP-------IAF 158
                    |....|::.||     |...:  |:|.::|.|...|     :|.|.|       |..
 Frog    86 TESFVQKWLRVFSLVIYICLLTIGYVLTYDSSVVHAWDQVPFFLFITFSVYTMLPLGMQACLIVS 150

  Fly   159 VKNGRAYFLGLAVSLFYFGYMALIDKISTLDKVWELTAYGAYLFFLNMLCMFLSRFQEYNMRSGI 223
            :.:|.::.:.:::::       ::...|.....::|.| .|.:|....|   :..:.:|:|:...
 Frog   151 IISGISHIIVISITV-------VLSSGSNDAIAFQLMA-NAVIFLCGNL---MGAYHKYHMQDAS 204

  Fly   224 LSRYQVVYQNLVFQMAM----KEEKALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLF 284
            ...|....:.:..:|.:    :::::||.|::||.::..::.||...:.|...|..|......|:
 Frog   205 RDLYSYTVKCIRIKMKLELKKRQQESLLLSVLPVYISMEMKLAIQDRLTETNDNRQPDNNFHSLY 269

  Fly   285 MEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGI 349
            ::.|..||||.||:|.||.|.:.....:||.:|:|||..||..|..|...|||.|||.|.||:|:
 Frog   270 VKRHQNVSILYADIVGFTRLASDCSPKELVVMLNELFGKFDQIAKENECMRIKILGDCYYCVSGL 334

  Fly   350 PSYFPTHANACVNQALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDI 414
            |...|.:|..||...||:.|..::|.:.....|::|:|||||.:|.|:|||.|||||:||.||.:
 Frog   335 PVSLPNNAKNCVKMGLDICEAIKQVREATGADINMRVGVHSGNVLCGVIGLRKWQFDVWSHDVSL 399

  Fly   415 TNRLESSGLPGMVHISSRTLGLLDNHYVYEEGTDTAKLDPLLQRSNLSTYLI------RSRLPNF 473
            .||:||:||||.|||:..||..::..|..|||....: ||.|:..|:.|:|:      .||:.|.
 Frog   400 ANRMESAGLPGRVHITEATLKHMNGAYDVEEGHGELR-DPYLKEMNIKTFLVIDPRAKNSRVKNN 463

  Fly   474 EDTDDLEDDNFS------LNDYRFSFSFSQDYEDI-QVKAQRDMILEVEHMPVNRV------QTC 525
            ..|....:|...      :..|..|:..::.:... |..|....:..|...|...:      :|.
 Frog   464 HLTRHRVNDGIKVRPSVRMTRYLESWGAARPFSHFDQTDASSTEVPTVNGKPKPEIPLKGMGRTV 528

  Fly   526 KIRRPMHRIAKEDINEEYRFH-------------------LESYY---LFTTFRSWRMEWSFNKM 568
            |..|.:    .:..|:|...|                   .:.:|   ||.|......|:...::
 Frog   529 KTERNV----SQKRNQEEELHDRMMNTIDGLSSAKPWFGKTDDFYGFLLFFTADGLEKEYRTFRI 589

  Fly   569 RDLLMKYSLGMMVFAGATIIAMDLLVKSEAMDYTMLFSLFLLILLPLLLASYKKLWLRGRRLSPI 633
            ..:...:....::|  ..|..:.:||...:.:..:.|.:..:::|.:||..|..   :..|....
 Frog   590 PCIQSYFLCASLIF--LCIFLIQILVMPRSANLGISFGVVSVLILWVLLICYVD---KCARFCNE 649

  Fly   634 TQPTFFLSRWFIKASDLIEKSVFVRIPLAIMVLFLLYVMS------SETVFSCDIARLELEIINS 692
            ..|   .||:.....::||....:|:||..:.|..|.::|      .:|:.:|:.:.:..|   |
 Frog   650 NAP---FSRFLCSLVEMIETRPSLRVPLVALTLGSLLIISIVNLPLDQTLQTCNTSSIATE---S 708

  Fly   693 ELHNLRPQMLCFMPWGVTYAVVIVLSLMLVIIGIPLIIKLGVGL---AILGSHVITVHAYYGFAF 754
            :..::        |:   |....:|.|:...:.:.:..:|.:.|   |....:||..|.:... |
 Frog   709 QCQSI--------PY---YVYCCILGLVACSMFLRMCFELKILLLTAAFTAYNVIIFHTHSSI-F 761

  Fly   755 ERSQTTNIGVTSSL--AHSWYMVAFFIVVVVREGYLNYILKASYFMSMCFEKKHELTKVKTRTIK 817
            ..:..::|||....  ...:|:..:::.:|:....:.|..:........|.|:.|..:......:
 Frog   762 RSNLNSSIGVLEDFQKMSCFYLSLYYLTLVLLARQVEYYSRLDCLWKRKFRKEDEEIETMENLNQ 826

  Fly   818 IIMANILPTHVAEVFKVRRRSDQ-LYYENFSQVAVMFATIENY-------EADKSG---LRALHE 871
            :::.|:||.|||..|....||:: ||::::..|.||||::..:       :.:|.|   ||.|:|
 Frog   827 LLLENVLPAHVAAYFIDDNRSNEDLYHQSYDCVCVMFASVPEFKVFYTECDVNKEGLECLRLLNE 891

  Fly   872 MICYFDELLVNYQSWYKIEKIKVMGWTYLAACGLHVDHYTDFSVSVPISTNRESDKLQKSGSVRF 936
            :|..|||||:. ..:..:||||.:|.||:||.||         .:.|...|::.:|
 Frog   892 IIADFDELLMK-PKFSGVEKIKTIGSTYMAATGL---------TATPGQENQDQEK--------- 937

  Fly   937 APMDGDEIMIKDLHPTQATTNEDDNTILVMTEFALNLLRILRDIRSKGIFFEKDSKLTG------ 995
                                  ....|.:..|:|:.|:                |||.|
 Frog   938 ----------------------QHALIGITVEYAMALM----------------SKLDGINRHSF 964

  Fly   996 ---SLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANVLRDFNIRC 1057
               .|::||.||||:|||:|..||.|||||:|||:||||.|||....|.|||.|..:|......|
 Frog   965 NNFRLRVGINHGPVIAGVIGAKKPQYDIWGNTVNVASRMESTGELGKIQVTEETCQILEGLGYSC 1029

  Fly  1058 TYRGMTFVKGVGQVPTYLVDLD 1079
            ..||...|||.|::.||.|..|
 Frog  1030 ECRGFINVKGKGELRTYFVCTD 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32301	NP_728724.2	AcyC	51..445	CDD:441717	126/419 (30%)
		Nucleotidyl_cyc_III	283..439	CDD:448371	75/155 (48%)
		AcyC	681..1076	CDD:441717	115/419 (27%)
		Nucleotidyl_cyc_III	841..1076	CDD:448371	84/253 (33%)
adcy7	NP_001106549.1	AcyC	64..455	CDD:441717	123/402 (31%)
		Guanylate_cyc	268..418	CDD:425528	73/149 (49%)
		Adcy_cons_dom	483..590	CDD:461877	17/110 (15%)
		Guanylate_cyc	851..1048	CDD:425528	84/253 (33%)