Protein Alignment ACXD and gucy1a1

DIOPT Version :9

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_001296458.1
• Gene: gucy1a1 / 550420
• ZFINID: ZDB-GENE-050417-230
• Length: 679
• Species: Danio rerio
• Alignment Length: 630
• Identity: 135/630 - (21%)
• Similarity: 234/630 - (37%)
• Gaps: 195/630 - (30%)

  Fly    10 EYNRSNPISLARTSSQAQTVQNEKNWEWSYLVRKCRNLELEDSYDLYMRRLRVGYLSLFIF---- 70
            :.:.|.|:  |.:|..:.|:.|.:.     |....:|..|:..  :.|..|::. |.|.:|
Zfish    93 QIDTSCPV--ACSSDVSHTLDNAEQ-----LSDVMKNYSLKTG--IPMDALKIS-LGLEVFRDCY 147

  Fly    71 ------IHVAVTVIHTLL-----LL-----TTPEIKYVYVDMVAYMC----SGLVIWVVLGVNFR 115
                  :.|....:|..|     ||     .||||:. |:...:.:|    .||     |.|.|.
Zfish   148 EEDGHILRVVGGALHDFLNSFNVLLKQSTPPTPEIQR-YIHQASILCLDKDPGL-----LTVYFF 206

  Fly   116 SELVSKH---GWVVYATSWLAVC--VMVLMDIGLNVYHATSHNDILNPIYDAYTLYAI------- 168
            :.|.|..   ..::.|.:.|..|  |.|.||:|      ...:..|...:..:.||::
Zfish   207 NPLPSTELFFSGIIQAAACLLYCTRVEVRMDVG------GKDSGALQADHQPHLLYSVVVRDGRS 265

  Fly   169 -------------------YMFMPVPYLL------------------------------------ 178
                               |...|...||
Zfish   266 LTPSPMRTHTSGDIPLSLLYSTFPFHILLDQEMGLLQIGDGLRRRLGRCRDGQRRPAFNEHFAIV 330

  Fly   179 QPFVLGSAVTFCYIINYSFVITAK-------DDNQMH-SILNEAIYLSCVNLLGIFFRLMRDIAL 235
            .|.:..|......::|..|::..|       |....| .:..:.|::|.::.|         :.|
Zfish   331 SPEIRASFQDILTMLNTQFLLRVKQHGASSADSPGKHMDLKGQMIFMSEMSAL---------LFL 386

  Fly   236 RTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIA----------DRLQEDVKNRIERSK--- 287
            .:..:|:.:.:           ..|.|.||.:|...|          .:.|:.:|.|:.::|
Zfish   387 GSPCVDKLEEL-----------TGRGLYLSDIPIHNALRDVVLVGEQTKAQDGLKKRLGKAKAAL 440

  Fly   288 QQHQQQSQVDLRRSAD----------SQTLKRWR-QPDHGTLFIEPHEDVTVLYADVVNYTHLTT 341
            :|..|..:.:.||:.:          :|.|  |: .|.....|    :.||||::|:|.:|.:.:
Zfish   441 EQAHQALEEEKRRTVELLFTIFPGNVAQRL--WQGLPVQAKKF----DHVTVLFSDIVGFTAICS 499

  Fly   342 TLDVKKLVEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDI 406
            .....::|..|.:|:.|||....|.:|.:::.:||.|....||...:..||.....:.|:|::..
Zfish   500 RCTPMQVVNMLSELYTRFDHHCGELDVYKVETIGDAYCVAGGLHKESPTHAVQIALMALKMMELS 564

  Fly   407 RDVREKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSL 471
            .:|.......|.||||:|||.||:||:|....::.::..:|.:||:.|:.....:::||..|..|
Zfish   565 DEVTTPMGEVIRMRIGIHSGSVLAGVVGVKMPRYCLFGNNVTLANKFESCSLPRKINVSPTTYRL 629

  Fly   472 LDGEYFFEDGTE-----KARED-----PV--------LQKHGIRT 498
            |      :|..|     :.|||     |.        ||.|..:|
Zfish   630 L------KDCPEFTLIPRTREDLPPNFPTDIPGVCYFLQAHDQKT 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	61/350 (17%)
		CYCc	254..476	CDD:214485	66/245 (27%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	57/196 (29%)
		CYCc	856..1117	CDD:214485
		Nucleotidyl_cyc_III	878..1142	CDD:299850
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:285003	31/210 (15%)
		CYCc	449..635	CDD:214485	55/197 (28%)
		Guanylate_cyc	476..647	CDD:278633	53/180 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900